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2008 Jan 22
2
extension to nlme self start SSmicmen?
Dear list, Has anyone created a version of SSmicmen that allows testing for group differences? The basic Michaelis-Menten equation is: (Bmax * X) / (Kd + X). The nlme package allows modeling of random effects for Bmax and Kd as needed, but I curious how I can build in group differences? I have receptor binding data for strains of mice, and following Pinheiro and Bates' lead in their