Displaying 3 results from an estimated 3 matches for "fdrs".
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drs
2005 Sep 19
5
FDR analyses: minimum number of features
Dear List,
We are planning a genotyping study to be analyzed using false discovery
rates (FDRs) (See Storey and Tibshirani PNAS 2003; 100:9440-5). I am
interested in learning if there is any consensus as to how many
features (ie. how many P values) need to be studied before reasonably
reliable FDRs can be derived. Does anyone know of a citation where
this is discussed?
Bill Dupont
Willi...
2005 Sep 22
0
FW: FDR analyses: minimum number of features
Dear Dr. Graves
Many thanks for your response. FDRs and their associated q values do
differ from Type I error rates and P values (See Storey and Tibshirani
PNAS 2003;100:9440-5). It is an approach that is rapidly gaining
popularity in the analysis of genomic data where we have massive numbers
of covariates measured on a comparatively modest number...
2013 Mar 18
2
Fit a mixture of lognormal and normal distributions
...R package/way of doing this or has any hints that would help me coding it from scratch (EM+writing down the formulae for ML? but... would this really be better than using a "more-advanced-already-available-package-made-by-pros"?).
The objective is to estimate threshold values at specific FDRs. (some help with that would also be most helpful.)
Thanks to all in advance!To'
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