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2007 Dec 26
1
nlme package
...the syntax of the NLME package that I am not aware. 
 
This is the R script:
 
library(nlme)
 
treat=as.factor(c(1,2,1,2,1,2,1,2))
mouse=as.factor(c(1,1,2,2,3,3,4,4))
time=as.factor(c(1,1,1,1,2,2,2,2))
mouse.anova=function(vec){lme(vec~treat+time+treat*time,random=~1|mouse/time)} 
 
lme.out=apply(exprmat,1,mouse.anova)
 
This is the ERROR message:
 
Error in lme.formula(vec ~ treat + time + treat * time, random = ~1 |  : 
  nlminb problem, convergence error code = 1
  message = singular convergence (7)
 
I will appreciate your help in pointing mistakes in this R script. 
Thank you very much.
Roger...