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2011 Oct 08
1
HWEBayes, swapping the homozygotes genotype frequencies
...f nvec, I received totally different Bayes factor: > > HWETriangBF2(nvec=c(2,10,88)) [1] 5.710153 > In my understanding, defining the genotype frequency as n11 or n22 are arbitrary. So I was expecting the same value of Bayes factor. This is the case for conjugate Dirichlet prior: >DirichNormHWE(nvec=c(88,10,2), c(1,1))/DirichNormSat(nvec=c(88,10,2), c(1,1,1)) [1] 1.542047 >DirichNormHWE(nvec=c(2,10,88), c(1,1))/DirichNormSat(nvec=c(2,10,88), c(1,1,1)) [1] 1.542047 Could you explain why the HWETriangBF2 is returining completely different values of Bayes Factor?? -- View this message...