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2004 Jan 23
0
cmptl_analy.R
Dear Michael, One key is adjustment of nls optimizer tolerance. I notice it has to be higher than usual, but, I recovered your noisy "known" parameter values with an error of K1 (-7%) and k1 (-6%): #### Miller problem with Dalgaard modifications ## Linares 1/22/2004 ## Solution 1 nls(noisy ~ lsoda(xstart, time, one.compartment.model, c(K1=K1, k2=k2))[,2], data=C1.lsoda,