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2006 Jun 05
3
Fastest way to do HWE.exact test on 100K SNP data?
Hi everyone,
I'm using the function 'HWE.exact' of 'genetics' package to compute p-values of
the HWE test. My data set consists of ~600 subjects (cases and controls) typed
at ~ 10K SNP markers; the test is applied separately to cases and controls. The
genotypes are stored in a list of 'genotype' objects, all.geno, and p-values are
calculated inside the loop over all