Displaying 3 results from an estimated 3 matches for "biallelic".
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allelic
2010 Feb 28
1
Combining 2 columns into 1 column many times in a very large dataset
...)), disType = rbinom(n, 1, .2),
rs123=c(1,3,1,3,3,1,1,1,3,1), rs123.1=rep(1, n),
rs157=c(2,4,2,2,2,4,4,4,2,2),
rs157.1=c(4,4,4,2,4,4,4,4,2,2), rs132=c(4,4,4,4,4,4,4,4,2,2),
rs132.1=c(4,4,4,4,4,4,4,4,4,4))
Thus, there are a few columns of basic demographic info and then the rest of
the columns are biallelic SNP info. Ex: rs123 is allele 1 of rs123 and
rs123.1 is the second allele of rs123.
1) I need to merge all the biallelic SNP data that is currently in 2 columns
into 1 column, so, for example: rs123 and rs123.1 into one column (but
within the dataset):
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2) I need to i...
2009 Feb 09
0
Generating missingness on SNP data
Dear all,
I generated a dataset with 500 unrelated individuals and 10 biallelic
SNPs. From this dataset,I would like to create data with 5% missingness on
genotype information at random and also data with 5% genotyping error.
Can someone help me with how I can do it.
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2012 Sep 10
1
Calculating Linkage Disequilibrium for Microsatellite Markers?
...ci. Importantly, my loci are microsatellites and have up to 30
alleles per locus. Do you know of any R packages that can either (1)
calculate measures of LD directly or (2) test for the presence of LD within
a statistical framework? Every package I have run across seems to be only
able to handle biallelic (e.g., SNP) data. I have
searched unsuccessfully both at CRAN and Bioconductor.
Many thanks for any help you can provide,
Mark Christie
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