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...itely expressed genes compare A to B situation. I got this data(this is a part of data) from whole organism , and each number means each expression values (that means, we could think 'a' gene is 13 in A situation, and it turns 30 in B situation) To findout probability, I'm going to use Audic - Claverie Method. ( The significance of digital gene expression profiles. 1997) But using this equation p(x|y), I have to calculate (x+y)! first. but I can't calculate (157+221)! or (666+1387)! in R. That's probabily the handling problem of huge number, How could I calculate p value in...

Does anybody have (or know of) a command line application that would: ) Eliminate pops and other random loud noises. ) Trim leading and trailing silence. ) Trim pauses exceeding x milliseconds to y milliseconds. ) Normalize what's left. I know about normalize and have figured out how to trim leading and trailing silence in sox, but I'm looking for more :) Thanks in advance,

...scape digit is pressed. Also, the file length appears to be consistent with NOT cutting off the overdub. So it seems like the second RECORD FILE command actually runs to completion propertly, but does NOT actually add any samples to the file after the length of the original recording. This might be Audicity, however, just refusing to show data past the end of the sample size as read in the wav file header if, e.g. the header is not updated at the end of the second call. So, the my real question is whether or not these are known bugs, or if perhaps I've configured something wrong. Has anybody a...