search for: angiotensinogen

Hi, I have taken one microarray experiment and trying to implement same statistical measures what they have done.I have taken datasets from GEO platform with accession number GSE1557. In the experiment,about half of double transgenic rats (dTGR) over-expressing the human renin and angiotensinogen genes die by age 7 weeks of terminal heart failure (THF); the other (preterminal) half develops cardiac damage, but survives to week 7. The aim of the study was to elucidate the difference in cardiac gene expression of dTGR with THF compared to dTGR showing compensated cardiac hypertrophy, but not...