search for: allelements

Dear All, The following code extracts from NCBI very nice output for ONE allele of a SNP (often the allele with the second largest frequency - usually termed the minor allele). It gives an average minor allele frequency from all NCBI sources (which is what I want, except I'd like the addition of data for all the other alleles of one SNP) plus a table of minor allele frequencies from each

Hi people, I have made some progress trying to work out how to solve this problem but I have got a bit stuck - sorry if this turns out to be a simple exercise . . Allelic Differentiation (AD) in genetics measures the number of different alleles between (say) two populations eg: Organisms in Pop 1 have alleles: a, b, c, d, e Organisms in Pop 2 have alleles: b, b, c, d, e Different

#Hello, #I have three data frames, X,Y and Z with two columns each and different numbers of rows. # creation of data frame X X.alleles <- c(1,5,6,7,8) X.Freq <- c(0.35, 0.15, 0.05 , 0.10, 0.35) Loc1 <- cbind( X.alleles,X.Freq) X <- data.frame(Loc1) #creation of data frame Y Y.alleles <- c(1,4,6,8) Y.Freq <- c(0.35, 0.35, 0.10, 0.20 )

Hi all, [this is a bit hard to describe, so if my initial description is confusing, please try running my code below] #WHAT I'M TRYING TO DO I'd appreciate any help in trying to speed up some code. I've written a script that converts a matrix of integers (usually between 1-10,000 - these represent allele names) into two new matrices of normally distributed values (representing

I have a vector: alleles.present<-c("D3", "D16", ... ) The alleles present changes given the case I'm dealing with - i.e. either all of the alleles I use for my calculations are present, or some of them. Depending on what alleles are present, I need to make matrices and do calculations on those alleles present and completely disregard any formula or other use of the

Hello All, Once again thanks for all of the help to date. I am climbing my R learning curve. I've got a few more questions that I hope I can get some guidance on though. I am not sure whether the etiquette is to break up multiple questions or not but I'll keep them together here for now as it may help put the questions in context despite the fact that the post may get a little long.

Hello R-help community, I have another question about filtering datasets. Please consider the following "toy" data matrix example, called "x" for simplicity. There are 20 different individuals ("ID"), with information about the alleles (A,T, G, C) at six different loci ("Locus1" - "Locus6") for each of these 20 individuals. At any single locus

The "genetics" package for handling single-locus genetic data is now available on CRAN in both source and Windows binary formats. The purpose of this package is to make it easy to create and manipulate genetic information, and to facility use of this information in statistical models. The library includes classes and methods for creating, representing, and manipulating genotypes

The "genetics" package for handling single-locus genetic data is now available on CRAN in both source and Windows binary formats. The purpose of this package is to make it easy to create and manipulate genetic information, and to facility use of this information in statistical models. The library includes classes and methods for creating, representing, and manipulating genotypes

Hello, I have two data frames, X and Y, with two columns each and different numbers of rows. # creation of data frame X Loc1.alleles <- c(1,5,6,7,8) Loc1.Freq <- c(0.35, 0.15, 0.05, 0.10, 0.35) Loc1 <- cbind( Loc1.alleles,Loc1.Freq) X <- data.frame(Loc1) #creation of data frame Y Loc2.alleles <- c(1,4,6,8) Loc2.Freq <- c(0.35, 0.35,

Hello, In a case control study how to calculate the risk allele or score allele. Regards GRR [[alternative HTML version deleted]]

I know that there are quite a few packages out that there for cluster analysis. The problem that I am facing is finding a package that will not incorporate all my samples into clusters but just the samples that fit a threshold (that I have not set yet and may need help finding the right level) for genotyping. It should be able to "no call" samples outside the clusters. It also needs to

Dear R user: I am studying the allele data of two populations. the following is the data: a1 a2 a3 a4 a5 a6 a7 a8 a9 a10 a11 a12 a13 a14 a15 a16 a17 pop1 0.0217 0.0000 0.0109 0.0435 0.0435 0.0000 0.0109 0.0543 0.1739 0.0761 0.1413 0.1522 0.1087 0.0870 0.0435 0.0217 0.0109 pop2 0.0213 0.0213 0.0000 0.0000 0.0000 0.0426 0.1702 0.2128 0.1596 0.1809 0.0957 0.0745 0.0106

Hi everyone, I'm using the function 'HWE.exact' of 'genetics' package to compute p-values of the HWE test. My data set consists of ~600 subjects (cases and controls) typed at ~ 10K SNP markers; the test is applied separately to cases and controls. The genotypes are stored in a list of 'genotype' objects, all.geno, and p-values are calculated inside the loop over all

Hi all, We are using two methods to identify SNPs. One is based on resequencing the genome and aligning the reads to the sequenced genome to identify SNPs (data available for 44 individuals). Another is based on SNP array with selected loci (30000 loci, 870 individuals). I want to compare the results from the resequencing based minor allele frequency and Array based minor allele frequency.

Dear R listers, I have a data file looks like the following: Testing marker: s_1 --------------------------------------------- Allele df(0) -LnLk(0) df(T) -LnLk(T) ChiSq p 3 7995 29320.30 7994 29311.85 16.90 4e-05 (2229/8000 probands) Testing marker: s_2 --------------------------------------------- Allele df(0)

I am involved in a study where, as in most of life, men demonstrate themselves to be recalcitrant. So while we have many probands and most of their mothers we only have about 50% of the trios being complete. I have been running tdt and trio.types. It appears as if it is ignoring the duos. Sometimes a duo can be informative. For instance Father ..missing Mother 1/2 Proband 1/1 This duo shows that

Has something changed in R that requires an update in the genetics package by Gregory Warnes? I am using R version 2.5.0 This used to work > summary(founders[,59]) to prove that it is a genotype class > class(founders[,59]) [1] "genotype" "factor" Now when I issue the command: > summary(founders[,59]) I get: Error in attr(retval, "which") <- which :

I am about one step away from heaven on earth. I think only one step! I am using dgc.genetics to run a TDT test on thousands of genetic loci. I have learnt (through the help of others on this mailing list) to send the complex output to useful data frames which in turn allow me to look at the big picture and screen the thousands of loci. Resultdt<-lapply(PGWide[,240:290], tdt) the above

I have been merrily using the genetics package and more specifically have been using the makeGenotypes and genotypes function. I check my accomplishments by going > class(g2) [1] "genotype" "factor" and likewise > class(g1) [1] "genotype" "factor" Yet when I execute a command such as allele count I get this > allele.count(g1) D I [1,]