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2005025
2012 Oct 31
0
combined dependent pvalue
...All,
I am trying to combine dependent p-values in R. May you please help me with
this?
For independent pvalue combination, one of the popular way is fisher's
method which I found the R code here
(http://r.789695.n4.nabble.com/fisher-s-posthock-test-or-fisher-s-combination-test-td2195964.html#a2305025):
fisher.comb <- function (pvalues)
{
df=length(pvalues)
ch2=(-2*sum(log(pvalues)))
return pchisq(ch2, df=df, lower.tail=FALSE)
}
For combination of dependent p-value, I could not find any R code here but
there is a method from Brown
(http://en.wikipedia.org/wiki/Extensions_of_Fisher%2...