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Please forgive a statistics question. I know that a simple bivariate linear regression, y=f(x) or in R parlance lm(y~x) can be solved using the variance-covariance matrix: beta(x)=covariance(x,y)/variance(x). I also know that a linear regression with multiple independent variables, for example y=f(x,z) can also be solved using the variance-covariance matrix, but I don't know how to do this.