Belgers, V. (Vera)
2020-Sep-14 11:54 UTC
[R] question including crossover trials in meta-analysis
Dear sir/madam, Thank you in advance for taking the time to read my question. I am currently trying to conduct a meta-analysis combining parallel and crossover trials. According to the Cochrane Handbook, I can include crossover trials by using t-paired statistics. So far, I have managed to conduct a meta-analysis and forest plot of the parallel trials using the dmetar package, but I did not succeed in including the crossover trials. I do have the raw data of most of these crossover trials. Does anybody know how to add crossover trials to the meta-analysis? With kind regards, Vera Belgers ______________________________________________________ VUmc disclaimer : www.vumc.nl/disclaimer AMC disclaimer : www.amc.nl/disclaimer
Bert Gunter
2020-Sep-14 19:14 UTC
[R] question including crossover trials in meta-analysis
Did you first try a web search? -- you should always do this before posting here. "meta-analysis in R" brought up this: https://CRAN.R-project.org/view=MetaAnalysis Have you looked at this task view yet? Bert Gunter "The trouble with having an open mind is that people keep coming along and sticking things into it." -- Opus (aka Berkeley Breathed in his "Bloom County" comic strip ) On Mon, Sep 14, 2020 at 11:50 AM Belgers, V. (Vera) < v.belgers at amsterdamumc.nl> wrote:> Dear sir/madam, > Thank you in advance for taking the time to read my question. I am > currently trying to conduct a meta-analysis combining parallel and > crossover trials. According to the Cochrane Handbook, I can include > crossover trials by using t-paired statistics. So far, I have managed to > conduct a meta-analysis and forest plot of the parallel trials using the > dmetar package, but I did not succeed in including the crossover trials. I > do have the raw data of most of these crossover trials. > Does anybody know how to add crossover trials to the meta-analysis? > With kind regards, > Vera Belgers > ______________________________________________________ > VUmc disclaimer : www.vumc.nl/disclaimer > AMC disclaimer : www.amc.nl/disclaimer > > ______________________________________________ > R-help at r-project.org mailing list -- To UNSUBSCRIBE and more, see > https://stat.ethz.ch/mailman/listinfo/r-help > PLEASE do read the posting guide > http://www.R-project.org/posting-guide.html > and provide commented, minimal, self-contained, reproducible code. >[[alternative HTML version deleted]]
Marc Schwartz
2020-Sep-14 19:41 UTC
[R] question including crossover trials in meta-analysis
Hi, Bert has pointed you to some R specific packages for meta-analyses via the Task View. It sounds like you may need to first address some underlying conceptual issues, which strictly speaking, is off-topic for this list. That being said, a quick Google search came up with some possible resources, beyond the Cochrane reference: https://academic.oup.com/ije/article/31/1/140/655940 https://onlinelibrary.wiley.com/doi/abs/10.1002/jrsm.1236 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0133023 Perhaps with additional conceptual background, that might assist in enabling you to make use of the R packages that provide relevant functionality. Another option, if you want to stay with the dmetar package, would be to contact the package maintainer for some guidance relative to how to use the functionality in the package given your specific use case. Regards, Marc Schwartz> On Sep 14, 2020, at 3:14 PM, Bert Gunter <bgunter.4567 at gmail.com> wrote: > > Did you first try a web search? -- you should always do this before posting > here. > > "meta-analysis in R" brought up this: > > https://CRAN.R-project.org/view=MetaAnalysis > > Have you looked at this task view yet? > > > Bert Gunter > > "The trouble with having an open mind is that people keep coming along and > sticking things into it." > -- Opus (aka Berkeley Breathed in his "Bloom County" comic strip ) > > > On Mon, Sep 14, 2020 at 11:50 AM Belgers, V. (Vera) < > v.belgers at amsterdamumc.nl> wrote: > >> Dear sir/madam, >> Thank you in advance for taking the time to read my question. I am >> currently trying to conduct a meta-analysis combining parallel and >> crossover trials. According to the Cochrane Handbook, I can include >> crossover trials by using t-paired statistics. So far, I have managed to >> conduct a meta-analysis and forest plot of the parallel trials using the >> dmetar package, but I did not succeed in including the crossover trials. I >> do have the raw data of most of these crossover trials. >> Does anybody know how to add crossover trials to the meta-analysis? >> With kind regards, >> Vera Belgers
Belgers, V. (Vera)
2020-Sep-15 06:59 UTC
[R] question including crossover trials in meta-analysis
Dear mr. Schwartz and mw Gunter, Thank you both for your reply. I did google but did not find these sources, so thank you. With kind regards, Vera Belgers ________________________________ Van: Bert Gunter <bgunter.4567 at gmail.com> Verzonden: maandag 14 september 2020 21:14 Aan: Belgers, V. (Vera) <v.belgers at amsterdamumc.nl> CC: r-help at R-project.org <r-help at r-project.org> Onderwerp: Re: [R] question including crossover trials in meta-analysis Did you first try a web search? -- you should always do this before posting here. "meta-analysis in R" brought up this: https://CRAN.R-project.org/view=MetaAnalysis<https://eur04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fcran.r-project.org%2Fview%3DMetaAnalysis&data=02%7C01%7Cv.belgers%40amsterdamumc.nl%7C460c6129ebd54ce61bb308d858e27bae%7C68dfab1a11bb4cc6beb528d756984fb6%7C0%7C0%7C637357077046991635&sdata=wtUat277Ectic3FwPyRh92uhm7Am%2FAvsam97590UJ0o%3D&reserved=0> Have you looked at this task view yet? Bert Gunter "The trouble with having an open mind is that people keep coming along and sticking things into it." -- Opus (aka Berkeley Breathed in his "Bloom County" comic strip ) On Mon, Sep 14, 2020 at 11:50 AM Belgers, V. (Vera) <v.belgers at amsterdamumc.nl<mailto:v.belgers at amsterdamumc.nl>> wrote: Dear sir/madam, Thank you in advance for taking the time to read my question. I am currently trying to conduct a meta-analysis combining parallel and crossover trials. According to the Cochrane Handbook, I can include crossover trials by using t-paired statistics. So far, I have managed to conduct a meta-analysis and forest plot of the parallel trials using the dmetar package, but I did not succeed in including the crossover trials. I do have the raw data of most of these crossover trials. Does anybody know how to add crossover trials to the meta-analysis? With kind regards, Vera Belgers ______________________________________________________ VUmc disclaimer : www.vumc.nl/disclaimer<http://www.vumc.nl/disclaimer> AMC disclaimer : www.amc.nl/disclaimer<http://www.amc.nl/disclaimer> ______________________________________________ R-help at r-project.org<mailto:R-help at r-project.org> mailing list -- To UNSUBSCRIBE and more, see https://stat.ethz.ch/mailman/listinfo/r-help<https://eur04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fstat.ethz.ch%2Fmailman%2Flistinfo%2Fr-help&data=02%7C01%7Cv.belgers%40amsterdamumc.nl%7C460c6129ebd54ce61bb308d858e27bae%7C68dfab1a11bb4cc6beb528d756984fb6%7C0%7C0%7C637357077047001589&sdata=yv4KfT6v%2FaTfTEXar7PgjBuYsy6STJpZjsbeieMTpEU%3D&reserved=0> PLEASE do read the posting guide http://www.R-project.org/posting-guide.html<https://eur04.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.r-project.org%2Fposting-guide.html&data=02%7C01%7Cv.belgers%40amsterdamumc.nl%7C460c6129ebd54ce61bb308d858e27bae%7C68dfab1a11bb4cc6beb528d756984fb6%7C0%7C0%7C637357077047001589&sdata=YwGAWSIcazrcvZ%2B7sSC2CoaUvffAEh6Gt2dr45lweYo%3D&reserved=0> and provide commented, minimal, self-contained, reproducible code. [[alternative HTML version deleted]]