Good morning I'm trying to optimize (minimize actually) a response from a DOE with 4 factors. The 4 factors were built from a Latin Hypercube DOE design type. Then I proceeded this experiment on 28 different cases, so each case will include 2000 experiments. I would like to find the factor quartet that will minimize globally the response. How can I find it? I built the script shown below, and I take the eigen values from the rsm summary, but it's wrong, isn't it ? I hope it's clear :) Thank you in advance Regards I built the following script: setwd("C:/Folder") data <- read.table("File.txt",header=TRUE) str(data) summary(data) data$block <- rep(1:28, each=2000) library(rsm) subset <- seq(from=min(data$Case),to=max(data$Case),by=1) resu <- rsm(Response ~ block + SO(A,B,C,D),data=data[subset,]) summary(resu) The file looks like the following: Case A B C D Response 1 1.05243 1.32528 0.974352 1.03963 0.01615749 2 1.10323 1.055 0.937314 1.19282 0.017107937 3 1.12744 1.06457 0.772495 1.44226 0.016988281 4 1.17818 1.07334 1.40521 1.73733 0.016978022 5 1.17297 1.07055 0.910072 1.15935 0.017274737 6 1.14439 0.705105 0.91889 1.78162 0.01699969 7 1.0403 0.778101 1.02743 1.41937 0.017164506 8 1.0847 0.770317 1.16855 1.04109 0.017394582 9 1.03789 1.23609 1.43767 1.52393 0.015932553 10 1.12329 0.68861 1.23011 1.49413 0.01698659 ... 11 ... ... 2150 ... ... 55999 1.19111 1.48329 0.880659 1.82682 0.037803564 56000 1.11901 1.12973 0.523026 1.92828 0.038733914 -- View this message in context: http://r.789695.n4.nabble.com/RSM-in-R-optimize-minimize-a-response-tp4713256.html Sent from the R help mailing list archive at Nabble.com.