R sig jobs - Jul 2015 - Postdoctoral Position in Biostatistics/Bioinformatics

Job Title : Postdoctoral Position in Biostatistics/Bioinformatics



Background


The joint research unit between bioM?rieux, international leader in in
vitro diagnostic, and Hospices Civils de Lyon, second-largest University
Hospital Network in France, develops a research program dedicated to the
study of injury induced immunosuppression. This program aims at (i)
describing and understanding the mechanisms leading to post-injury immune
dysfunctions as well as their association with increased risk of
health-care associated infections or fatal outcomes, (ii) identifying and
developing innovative biomarkers that could help to monitor
immunosuppression and stratify patients in clinical trials.

Within this structure, a position funded for 2 years (post-doctoral or
equivalent) in bioinformatics and biostatistics is open for recruitment.



Job Description

Bioinformatics to analyze high-throughput datasets from transcriptomic such
as microarrays, RNA-seq.

Biostatistics and epidemiological analyses addressing the issue of
healthcare-associated infections and biomarker evaluation in case control
or cohort studies : multivariate analyses, survival studies, etc ...

The candidate will work as part of a multidisciplinary group of several
research teams with expertise in Immunology, Molecular Biology,
Transcriptomics, Biostatistics and BioInformatics.



Required qualifications

Highly motivated candidates must hold a Ph.D. or engineer degree with a
strong background in bioinformatics and in biostatistics. Strong skills in
routine biostatistics and bioinformatics tools (R statistical language,
python) are required. Expertise in transcriptomics is desirable. The
candidate should be able to communicate and work in English and also
preferably in French.



Contract duration:           funded for 2 years



Starting date:                    September 2015

Locations:                         France, Lyon



Scientific contact: To apply, send a cover letter (2 pages max), curriculum
vitae, and contact information for references to :

Dr. Fabienne Venet:        fabienne.venet at chu-lyon.fr

Dr. Julien Textoris :          julien.textoris at biomerieux.com

Dr. Sophie Blein :             sophie.blein at biomerieux.com



Publications

Elevated plasmatic level of soluble IL-7 receptor is associated with
increased mortality in septic shock patients. Demaret J, Villars-M?chin A,
Lepape A, Plassais J, Vallin H, Malcus C, Poitevin-Later F, Monneret G,
Venet F. Intensive Care Med. 2014 Aug;40(8):1089-96.


Low-dose hydrocortisone reduces norepinephrine duration in severe burn
patients: a randomized clinical trial. Venet F, Plassais J, Textoris J,
Cazalis MA, Pachot A, Bertin-Maghit M, Magnin C, Rimmel? T, Monneret G,
Tissot S. Crit Care. 2015 Jan 26;19:21.


A strategy to build and validate a prognostic biomarker model based on
RT-qPCR gene expression and clinical covariates. Tournoud M, Larue A,
Cazalis MA, Venet F, Pachot A, Monneret G, Lepape A, Veyrieras JB. BMC
Bioinformatics. 2015 Mar 28;16:106.

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