Hi, I have IRanges 1.13.8 installed: > sessionInfo() R Under development (unstable) (2011-11-21 r57721) Platform: x86_64-unknown-linux-gnu (64-bit) locale: [1] LC_CTYPE=en_CA.UTF-8 LC_NUMERIC=C [3] LC_TIME=en_CA.UTF-8 LC_COLLATE=en_CA.UTF-8 [5] LC_MONETARY=en_CA.UTF-8 LC_MESSAGES=en_CA.UTF-8 [7] LC_PAPER=C LC_NAME=C [9] LC_ADDRESS=C LC_TELEPHONE=C [11] LC_MEASUREMENT=en_CA.UTF-8 LC_IDENTIFICATION=C attached base packages: [1] stats graphics grDevices utils datasets methods base other attached packages: [1] IRanges_1.13.8 BiocGenerics_0.1.3 And, surprisingly, I have no problem installing a package that requires IRanges >= 1.13.9 (thru the Imports field): hpages at rhino1:~/HTSeqGenie/svn> grep IRanges RNASeqGenie/DESCRIPTION Imports: BiocGenerics (>= 0.1.3), IRanges (>= 1.13.9), hpages at rhino1:~/HTSeqGenie/svn> R-2.15 CMD INSTALL RNASeqGenie * installing to library ?/home/hpages/R-2.15/library? * installing *source* package ?RNASeqGenie? ... ** R ** inst ** preparing package for lazy loading ** help *** installing help indices ** building package indices ... *** tangling vignette sources ... ?RNASeqGenie.Rnw? ** testing if installed package can be loaded * DONE (RNASeqGenie) Thanks! H. -- Herv? Pag?s Program in Computational Biology Division of Public Health Sciences Fred Hutchinson Cancer Research Center 1100 Fairview Ave. N, M1-B514 P.O. Box 19024 Seattle, WA 98109-1024 E-mail: hpages at fhcrc.org Phone: (206) 667-5791 Fax: (206) 667-1319