Hi, i need to test the equality of proportions in a paired case, like here: after before + - + 10 14 - 5 53 So usually i use the mcnemar.test(stats). Due to mortality, I now got the problem that my sample sizes in both factors are not equal any more -- there are less cases in the "after" condition. I already learned that Ekbohm (1982) and Marascuilo adressed the problem conceptually, but I'm not that good at writing my own functions. Can anyone give me a hint what function/test/package in R to use? Thank you very much for your help, Christian -- Christian Montel Eligo GmbH - B??ro Berlin Friedrichstr. 90 D - 10 117 Berlin Fon (030) - 20 25 31 94 Fax (030) - 20 25 33 33 e - mail: christian.montel at eligo.de http://www.eligo.de/