Displaying 20 results from an estimated 1000 matches similar to: "Multiple endpoint (possibly group sequential) sample size calculation"
2009 Dec 17
2
SPLUS Seqtrial vs. R Packages for sequential clinical trials designs
Hello Everyone,
I’m a SAS user who has recently become interested in sequential clinical trials designs. I’ve discovered that the SAS based approaches for these designs are either too costly or are “experimental.” So now I’m looking for alternative software. Two programs that seem promising are SPLUS Seqtrial and R.
I recently obtained a 30 day trial for the SPLUS Seqtrial add-on and have
2009 Sep 08
0
Genentech Nonclinical Biostatistics Position in South San Francisco
Nonclinical Biostatistics position at Genentech, South San Francisco
September 3, 2009
Genentech has an opening for a full time position in its Nonclinical
Biostatistics group, located in South San Francisco, CA.
The nonclinical group currently consists of ten MS and PhD level
statisticians and mathematicians, plus one programmer, who work with
approximately 1,000 scientists, engineers, and
2011 Jul 14
0
Nonclinical Biostatistics Opening at Genentech, South San Francisco
July 14, 2011
Genentech, A Member of the Roche Group, has an opening for a full time
position in its nonclinical biostatistics group located in South San
Francisco, CA.
The nonclinical group consists of statisticians who work with
scientists, engineers, and managers in research, drug discovery,
preclinical testing, process and product development, manufacturing,
and quality control. Statistical
2017 Sep 24
2
gsDesign Pocock & OBF boundary
Sorry for messed up text. Here it goes again:
I am learning to use the gsDesign package.
I have a question about Pocock and OBF boundary. As far as I can understand, these 2 boundaries require equal spacing between interim analyses (maybe this is not correct?). But looks like I can still use gsDesign to run an analysis based on unequal spacing:?
>
2004 Apr 26
2
Looking for help in calculating percentiles
Hi All:
I am working with a dataset on Arsenic toxicity, and I am trying to
calculate the 20th, 40th, 60th, 80th, and highest percentiles for a
variable, dietary Moisture (variable name dMoist).
The inbuilt function quantile(dMoist) would print 0, 25th, 50th, 75th, and
100th percentile. Does there exist a function that can calculate xth
percentile (where x = 10th, 20th, ... etc) values?
2017 Sep 22
2
gsDesign Pocock & OBF boundary
Hi,
I am learning to use your gsDesign package!?I have a question about Pocock and OBF boundary. As far as Iunderstand, these 2 boundaries require equal spacing between interim analyses(maybe this is not correct?). But I can still use gsDesign to run an analysisbased on unequal spacing:?gsDesign(k=2,test.type=2,timing=c(0.75,1),alpha=0.05,sfu='Pocock')Symmetrictwo-sided group sequential
2018 Aug 10
4
Efficacy of jitterentropy RNG on qemu-kvm Guests
Hello. I'm a distro maintainer and was wondering about the efficacy of
entropy daemons like haveged and jitterentropyd in qemu-kvm. One of the
authors of haveged [0] pointed out if the hardware cycles counter is
emulated and deterministic, and thus predictible. He therefore does not
recommend using HAVEGE on those systems. Is this the case with KVM's
counters?
PS. I will be setting VM CPU
2017 Sep 24
0
gsDesign Pocock & OBF boundary
Still failed.
The first secret is in your email program settings, to use Plain Text format (at least for emails you send to this mailing list).
The second secret tool to use is the reprex package to let you verify that your code example will do on our computers what it is doing on your computer before you send it to us. That will also involve giving us some sample data or referencing some data
2017 Sep 23
0
gsDesign Pocock & OBF boundary
> On 23 Sep 2017, at 01:32, array chip via R-help <r-help at r-project.org> wrote:
>
> Hi,
>
> I am learning to use your gsDesign package! I have a question about Pocock and OBF boundary. As far as Iunderstand, these 2 boundaries require equal spacing between interim analyses(maybe this is not correct?). But I can still use gsDesign to run an analysisbased on unequal
2005 Oct 12
1
Nonclinical Biostatistics Job Opening at Genentech in South San Francisco, CA
I hope that this job posting does not offend anyone. My sincere apologies if
it is inappropriate -- blame me, not my company.
-- Bert Gunter
Genentech Nonclinical Statistics
South San Francisco, CA
Genentech has an opening for a fulltime position in its nonclinical
biostatistics department, located in South San Francisco, CA.
The nonclinical group currently consists of seven MS and PhD
2002 Feb 08
3
Plotting multiple columns on same graph
I'd like to produce a series of simple line graphs for my methods class
that show the three questions used on a repeated survey to make up a
particular index. The data frame is:
> efficacy.df
year complicated havesay dontcare
1 1952 71 68 63
2 1954 NA NA NA
3 1956 64 71 71
4 1958 NA NA NA
5 1960
2008 Aug 22
1
Help on competing risk package cmprsk with time dependent covariate
Dear R users,
I d like to assess the effect of "treatment" covariate on a disease relapse risk with the package cmprsk.
However, the effect of this covariate on survival is time-dependent
(assessed with cox.zph): no significant effect during the first year of follow-up,
then after 1 year a favorable effect is observed on survival (step
function might be the correct way to say that ?).
2012 Feb 20
1
Triangular Test
Un texte encapsul? et encod? dans un jeu de caract?res inconnu a ?t? nettoy?...
Nom : non disponible
URL : <https://stat.ethz.ch/pipermail/r-help/attachments/20120220/1e5ae2c7/attachment.pl>
2011 Jul 12
16
The Witcher
hi! i have a small problem with the game, my energy is black and toxicity too.
Can you help me?
2009 Sep 06
2
[LLVMdev] should we stop using llvm-as/llvm-dis in tests?
On Sat, Sep 5, 2009 at 5:51 PM, Chris Lattner<clattner at apple.com> wrote:
>
> On Sep 5, 2009, at 1:53 PM, Nick Lewycky wrote:
>
>> A recent commit added the ability to opt and llc to read .ll files
>> directly. Should we go through and update the existing tests?
>
> Yes, I think that Dan is planning to do this.
... and it is definitely worth doing. On my system
2009 Jul 28
5
Summarising Data for Forrest Plots
I tried to post this a few times last week and it seems to have got stuck somehow so I'm trying from a different email in the hope that works. If somehow this has appeared on the list 20 tiems and I never saw any of them I apologize ;-)
I'm basically an R-newbie. But I am VERY computer literate. But this has me stumped...
All the examples for using the rmeta package to create a
2007 Apr 23
1
data recoding problem
Hi R experts,
I have a data recoding problem I cant get my head around - I am not that
great at the subsetting syntax. I have a dataset of longitudinal
toxicity data (for multistate modelling) for which I want to also want
to do a simple Kaplan-Meier curve of the time to first toxic event.
The data for 2 cases presently looks like this (one with an event, the
other without), with id representing
2018 Aug 16
1
Re: Efficacy of jitterentropy RNG on qemu-kvm Guests
Martin Kletzander:
> On Fri, Aug 10, 2018 at 08:33:00PM +0000, procmem wrote:
>> Hello. I'm a distro maintainer and was wondering about the efficacy of
>> entropy daemons like haveged and jitterentropyd in qemu-kvm. One of the
>> authors of haveged [0] pointed out if the hardware cycles counter is
>> emulated and deterministic, and thus predictible. He therefore does
2008 Apr 10
5
Extending Bluecloth/Redcloth
I''d like to extend bleucloth or redcloth to support custom tags, e.g. I
want to use markup like this:
[pubmed:18332676]
which shall be extended to:
<a href="http://www.ncbi.nlm.nih.gov/pubmed/18332676">Behav Pharmacol.
2008 Mar;19(2):121-128.</a>
Does anyone know, if this is possible and has some hints how to do
this?! I have not decided, wether I want to use
2003 Oct 28
1
Summary : Whitehead's group sequential procedures
Dear List,
I recently asked about any R implementations of Whitehead's methods for
sequential clinical trials. Here's the summary of answers so far :
1) There is no R public implementation of those methods
2) There exists an interest for such a package, which does things quite
different from Lan-deMets paradigm (shortly : Whitehead's methods allows
for unplanned interim analyses