similar to: Retrieving predictions after fitting a model

What am I failing to understand here? The script below works fine if the dataset being used is DNase1 <- DNase[ DNase$Run == 1, ] per the example given in help(nlrob). Obviously, I am trying to understand how to use nls and nlrob to fit curves to data using R. #package=DAAG attach(codling) plot(pobs~dose) #next command returns 'step factor reduced below min factor

I have a number of x, y observations (Time, Conc) for a number of Subjects (with subject number Subj) and Doses. I can plot the individual points with xyplot fine: xyplot(Conc ~ Time | Subj, Groups=Dose, data=myData, panel = function(x,y) { panel.xyplot(x, y) panel.superpose(???) # Needs more here } ) I also like to plot on

Hey, everyone, I am using proportional odds model for ordinal responses in dose-response experiments. For some samll data, SAS can successfully provide estimators of the parameters, but the built-in function polr() in R fails. Would you like to tell me how to make some change so I can use polr() to obtain the estimators? Or anyone can give me a hint about the conditions for the existance of MLE

Hi, I have recently been attempting to find the LD50 from two predicted fits (For male and females) in a Generalised linear model which models the effect of both sex + logdose (and sex*logdose interaction) on proportion survival (formula = y ~ ldose * sex, family = "binomial", data = dat (y is the survival data)). I can obtain the LD50 for females using the dose.p() command in the MASS

Hello to all, I'm a biologist trying to tackle a "fish" (Poisson Regression) which is just too big for my modest understanding of stats!!! Here goes... I want to find good literature or proper mathematical procedure to calculate a confidence interval for an inverse prediction of a Poisson regression using R. I'm currently trying to analyse a "dose-response"

Dear Colleagues, Our group is also working on implementing the use of R for pharmacokinetic compartmental analysis. Perhaps I have missed something, but > fit <- nls(noisy ~ lsoda(xstart, time, one.compartment.model, c(K1=0.5, k2=0.5)), + data=C1.lsoda, + start=list(K1=0.3, k2=0.7), + trace=T + ) Error in eval(as.name(varName), data) : Object

The following is evidence of what is surely an undesirable feature. The issue is the handling, in calls to model.frame(), of an explanatory variable that has been derived as an unclassed factor. (Ross Darnell drew this to my attention.) ## Data are slightly modified from p.191 of MASS > worms <- data.frame(sex=gl(2,6), Dose=factor(rep(2^(0:5),2)), +

Dear all, I can use the very nice drc package (multdrc()) to model and plot a dataframe containing dose and response values. I can also use predict.drc() to yield response values given a dose. I need to do the opposite, estimate a dose given the response. The general predict documentation seems to say that this is possible, but it does not appear that predict.drc has that capability.

Dear all, I am using R 3.4.3 on Windows 10. I am preparing some teaching materials and I'm having trouble matching the by-hand version with the R code. I have fitted a Cox model - let's use the ovarian data as an example: library(survival) data(ovarian) ova_mod <- coxph(Surv(futime,fustat)~age+rx,data=ovarian) If I want to make predict survival for a new set of individuals at 100

Hello-- I have a data for small population who took 1 drug at 3 different doses. I have the actual drug concentrations as well as predicted concentrations by my model. This is what I'm looking for: - Time vs Concentration by ID (individual plots), with each subject occupying 1 plot -- there is to be 9 plots per page (3x3) - Observed drug concentration is made up of points, and predicted drug

All, I have been able to successfully use the optim( ) function with "L-BFGS-B" to find reasonable parameters for a one-compartment open pharmacokinetic model. My loss function in this case was squared error, and I made no assumptions about the distribution of the plasma values. The model appeared to fit pretty well. Out of curiosity, I decided to try to use nlminb( ) applied to a

I have a dataset with event=death time (from medical examination until death/censoring) dose (given at examination time) Two groups are considered, a non-exposed group (dose=0), an exposed group (dose between 5 and 60). For some reason there is a theory of the dose increasing its effect over time (however it was only given (and measured) once = at the time of examination). I tested a model:

Thank you Frank and all for your advices. Here I attach the raw data from the Pawinski's paper. I have obtained permission from the corresponding Author to post it here for everyone. The only condition of use is that the Authors retain ownership of the data, and any publication resulting from these data must be managed by them. The dataset is composed as follows: patient number / MMF dose in

Dear R-help, I have fitted a glm logistic function to dichotomous forced choices responses varying according to time interval between two stimulus. x values are time separation in miliseconds, and the y values are proportion responses for one of the stimulus. Now I am trying to extrapolate x values for the y value (proportion) at .25, .5, and .75. I have tried several predict parameters, and they

I would like to know how R computes the probability of an event in a logistic model (P(y=1)) from the score s, linear combination of x and beta. I noticed that there are differences (small, less than e-16) between the fitting values automatically computed in the glm procedure by R, and the values "manually" computed by me applying the reverse formula p=e^s/(1+e^s); moreover I noticed

Question: after fitting a gamma function to some data, how do I get predicted values? I'm a SAS programmer, I new R, and am having problems getting my brain to function with the concept of "object as class ...". The following is specifics of what I am doing: I'm trying to determine the pdf from data I have created in a simulation. I have generated frequency counts

Hello all I have done some fitting of pnorm functions to dose-response data, so I could calculate EC50 values (dose where the response is 0.5). I used the nlm function for this, so I did not get any information about the confidence intervals of the fitted parameters. What would be a good way to do such a probit fit, or is there a package which I could use? Best regards Johannes Ranke

R-helpers, I am using the package "drc" to fit a 4 parameter logistic model. When I use the predict function to get prediction on a new dataset, I am not getting the requested confidence or prediction intervals. Any idea what is going on? Here is code to reproduce the problem: --- library(drc) # Fit model to existing dataset in package spinach.model <- drm(SLOPE~DOSE, data =

Hi! I want to use the DRC package in order to calculate the IC50 value of an enzyme inhibition assay. The problem is that the estimated ED50, is always out of the fitted curve. In the example below, I had a ED50 value of 2.2896, But when I predict the response level for this concentration I get a value of 45.71 instead of the expected value of 50. This is my data: #Dose unit is concentration

Hi - I am fitting a probit model using glm(), and the deviance and residual degrees of freedom are different depending on whether I use a binary response vector of length 80 or a two-column matrix response (10 rows) with the number of success and failures in each column. I would think that these would be just two different ways of specifying the same model, but this does not appear to be the case.