similar to: no "rcorrp.cens" in hmisc package

I have two alternative Cox models with C-statistics 0.72 and 0.78. My question is if 0.78 is significantly greater than 0.72. I'm using rcorrp.cens. I cannot find the U statistics in the output of the function. This is the output of the help example: > x1 <- rnorm(400) > x2 <- x1 + rnorm(400) > d.time <- rexp(400) + (x1 - min(x1)) > cens <- runif(400,.5,2) > death

Hi, I am trying to calculate net reclassification improvement (NRI) and Inegrated Discrimination Improvement (IDI) for a survival dataset to compare 2 risk models. It seems that the improveProb() in Hmisc package does this only for binary outcome, while rcorrp.cens() does take survival object, but doesn't output NRI or IDI. Can anyone suggest any other packages that can calculate NRI and IDI

Dear all, I am interested to evaluate reclassification using net reclassification improvement and Integrated Discrimination Index IDI after survival analysis (Cox proportional hazards using stcox). I search a R package or a R code that specifically addresses the categorical NRI for time-to-event data in the presence of censored observation and, if possible, at different follow-up time points. I

Hi R-users, I'm having some problems in using the Hmisc package. I'm estimating a cox ph model and want to test whether the drop in concordance index due to omitting one covariate is significant. I think (but I'm not sure) here are two ways to do that: 1) predict two cox model (the full model and model without the covariate of interest) and estimate the concordance index (i.e. area

Dear R-help, Would it be appropriate to do the following to calculate a p-value for the difference between c-ind of x1 and c-inx of x2 using the output from rcorrp.senc() > r<-rcorrp.senc(x1,x1,y) > pValue<-1-pnorm((r[11]-r[12])/(r[2]/r[5])*1.96) Osman O. Al-Radi, MD, MSc, FRCSC Chief Resident, Cardiac Surgery University of Toronto, Canada

Dear, I wanna to compare AUC generated by two distribution models using the same sample. The AUC for model 1 consists of two columns, column A for 0/1 and column B for probability, eahc with the same row number of 3000. The AUC for model 2 consists of two columns, column A for 0/1 and column B for probability, eahc with the same row number of 10000 rows. I am wondering what value I should put

Dear R-listers, I am an MD and clinical epidemiologist developing a measure of comorbidity severity for patients with liver disease. Having developed my comorbidity score as the linear predictor from a Cox regression model I want to compare the discriminative ability of my comorbidity measure with the "old" comorbidity measure, Charlson's Comorbidity Index. I have nearly 10,000

I am reposting my message from April 8th because I never received a response to the original post: Dear R-listers, I am an MD and clinical epidemiologist developing a measure of comorbidity severity for patients with liver disease. Having developed my comorbidity score as the linear predictor from a Cox regression model I want to compare the discriminative ability of my comorbidity measure with

Dear, I wanna to compare AUC generated by two distribution models using the same sample. The AUC for model 1 consists of two columns, column A for 0/1 and column B for probability, eahc with the same row number of 3000. The AUC for model 2 consists of two columns, column A for 0/1 and column B for probability, eahc with the same row number of 10000 rows. I am wondering what value I should put

Does anyone know of an R-function or method to compare two C-statistics (Harrells's C - rcorr.cens) obtained from 2 different models in partially paired datasets (i.e. some similar and some different cases), with one continuous independent variable in each separate model? (in a survival analysis context)? I have noticed that the rcorrp.cens function can be used for paired data. Thanks

Dear R-help, This is an example in the {Hmisc} manual under rcorr.cens function: > set.seed(1) > x <- round(rnorm(200)) > y <- rnorm(200) > round(rcorr.cens(x, y, outx=F),4) C Index Dxy S.D. n missing uncensored Relevant Pairs Concordant Uncertain 0.4831 -0.0338 0.0462 200.0000

Hi, I am trying to simulate a regression on survival data under a few conditions: 1. Under different error distributions 2. Have the error term be dependent on the covariates But I'm not sure how to specify either conditions. I am using the Design package to perform the survival analysis using the survreg, bj, coxph functions. Any help is greatly appreciated. This is what I have so far:

Dear list, I am trying to work out how the improveProb() function works and how to interpret the results, and I have a few questions. I would be grateful if anyone could shed some light on these. in the Net Reclassification Improvement section of the output, is the 2P column the two-sided p-value for the differences in classification? So if a limit is set at 0.05, then lower values indicate

Hi, I'm trying to calculate 95% confidence interval of C statistic of logistic regression model using rcorr.cens in rms package. I wrote a brief function for this purpose as the followings; CstatisticCI <- function(x) # x is object of rcorr.cens. { se <- x["S.D."]/sqrt(x["n"]) Low95 <- x["C Index"] - 1.96*se Upper95 <- x["C

Hi R experts, I am trying to do a prognostic model validation study, using cancer survival data. There are 2 data sets - 1500 cases used to develop a nomogram, and another of 800 cases used as an independent validation cohort. I have validated the nomogram in the original data (easy with the Design tools), and then want to show that it also has good results with the independent data using 60

Dear r-helpers! I want to classify my vegetation data with hierachical cluster analysis. My Dataset consist of Abundance-Values (Braun-Blanquet ordinal scale; ranked) for each plant species and relev?. I found a lot of r-packages dealing with cluster analysis, but none of them is able to calculate a distance measure for ranked data. Podani recommends the use of Goodman and Kruskals' Gamma for

I am using the rcorr.cens function from the Hmisc package and the time-dependent ROC curve obtained using tdrocc in the survcomp package. I understand that the C statistic from rcorr.cens has to be subtracted from 1 if high values of the risk variable lower survival. Given that I wonder what the connection is between that C statistic and the AUC from the tdrocc object. If they are substantially

Hello R Community, I'm continuing to work through logistic regression (thanks for all the help on score test) and have come up against a new opposition. I'm trying to compute Somers Dyx as some suggest this is the preferred method to Somers Dxy (Demaris, 1992). I have searchered the [R] archieves to no avail for a function or code to compute Dyx (not Dxy). The overview of Hmisc has

Dear R-help How can one get survplot() to place the number at risk just below the survival curve as opposed to the default which is just above the x-axis? I tried the code bellow but the result is not satisfactory as some numbers are repeated several times at different y coordinates and the position of the n.risk numbers corresponds to the x-axis tick marks not the survival curve time of

Hello, Is there is any R function computes the AUC for paired data? Many thanks, Samuel [[alternative HTML version deleted]]