similar to: nls vs nlme: parameter constraints

Dear Thomas Lumley, and R-help list members, I have read your article "Network meta-analysis for indirect treatment comparisons" (Statist Med, 2002) with great interest. I found it very helpful that you included the R code to replicate your analysis; however, I have had a problem replicating your example and wondered if you are able to give me a hint. When I use the code from the

Hi, I asked this on mixed model mailing list, but that list is not very active, so I'd like to try the general R mailing list. Sorry if anyone receives the double post. Hi, I have a dataset of animals receiving some eye treatments. There are 8 treatments, each animal's right and left eye was measured with some scores (ranging from 0 to 7) 4 times after treatment. So there are

Dear r-helpers, Spencer Graves and Manual Morales proposed the following methods to simulate p-values in lme4: ************preliminary************ require(lme4) require(MASS) summary(glm(y ~ lbase*trt + lage + V4, family = poisson, data = epil), cor = FALSE) epil2 <- epil[epil$period == 1, ] epil2["period"] <- rep(0, 59); epil2["y"] <- epil2["base"]

My question concerns the logic behind hypothesis tests for fixed-effect terms in models fitted with lme. Suppose the levels of Subj indicate a grouping structure (k subjects) and Trt is a two-level factor (two treatments) for which there are several (n) responses y from each treatment and subject combination. If one suspects a subject by treatment interaction, either of the following models seem

I have three columns of data, Xc, Trt and fish. This was a repeated measures design with 6 measurements taken from each of 5 fish. Xc is the actual measurement, Trt is the treatment, and fish is the fish number. Data can be seen below (hopefully it is in the column format). I would like to look for differences between treatments in a repeated measures format. I used the following code

Hi al, I have a dataset (see attached), which basically involves 4 treatments for a chemotherapy drug. Samples were taken from 2 biopsy locations, and biopsy were taken at 2 time points. So each subject has 4 data points (from 2 biopsy locations and 2 time points). The objective is to study treatment difference.? I used lme to fit a mixed model that uses "biopsy.site nested within pid"

Hello list, I'm doing a bootstrap analysis where some models occasionally fail to converge. I'd like to automate the process of restricting AIC to the models that do converge. A contrived example of what I'd like to do is below: resp <- c(1,1,2) pred <- c(1,2,3) m1 <- lm(resp~pred) m2 <- lm(resp~poly(pred,2)) m3 <- lm(resp~poly(pred,3)) # Fails, obviously ## Some

Hello, I am trying to run a mixed effects nested ANOVA but none of my codes are giving me any meaningful results and I am not sure what I am doing wrong. I am a new user on R and would appreciate some help. The experimental design is that I have some frogs that have been exposed to three acoustic Treatments and I am measuring neural activity (egr), in 12 brain regions. Some frogs also called

Let's say I have the following string: str <- "P = 0.0, T = 0.0, Q = 0.0" I'd like to find a function that generates the following object from 'str'. list(P = 0.0, T = 0.0, Q = 0.0) Thanks! -- http://mutualism.williams.edu

Dear, I have a dataset with 4 subjects (see ID in example), and 4 treatment (see TRT in example) which are tested on 2 locations and in 3 blocs. By using Lattice dotplot, I made a graph that shows the raw data per location and per bloc. In that graph, I would like to have a reference line per bloc that refers to the first treatment (T1). However, I can not find how to do that. I can make

Dear friends - I'm having troubles with nlme fitting a simplified model as shown below eliciting the error Error in chol.default((value + t(value))/2) : ? the leading minor of order 1 is not positive definite - I have seen the threads on this error but it didn't help me solve the problem. The model runs well in brms and identifies the used parameters even with fixed effects for TRT?

Hi there, The following data is obtained from a long-term experiments. > mydata <- read.table(textConnection(" + y year Trt + 9.37 1993 A + 8.21 1995 A + 8.11 1999 A + 7.22 2007 A + 7.81 2010 A + 10.85 1993 B + 12.83 1995 B + 13.21 1999 B + 13.70 2007 B + 15.15 2010 B + 5.69 1993 C + 5.76 1995 C + 6.39 1999

Dear R users, I'm pretty new on using lmer package. My response is binary and I have fixed treatment effect (2 treatments) and random center effect (7 centers). I want to test the effect of treatment by fitting 2 models: Model 1: center effect (random) only Model 2: trt (fixed) + center (random) + trt*center interaction. Then, I want to compare these 2 models with Likelihood Ratio Test.

Hello list members, I'm looking for a way to force the results of a crosstabulation to be square - that is, to include 0 values. For example: table(letters[1:4],letters[c(1:3,3)]) yields: a b c a 1 0 0 b 0 1 0 c 0 0 1 d 0 0 1 I would like to return: a b c d a 1 0 0 0 b 0 1 0 0 c 0 0 1 0 d 0 0 1 0 Any suggestions? Thanks! -- Manuel A. Morales

Hi all! I have 4 treatments on 5 animals Treat1 Treat2 Treat3 Treat4 Animal1 36 37 35 39 Animal2 33 34 36 37 Animal3 37 35 33 38 Animal4 34 36 34 35 Animal5 35 36 33 36 I use an Anova and i try to verify calcul So i retrieve: DF SS

Dear R - Users I have some problems fitting a linear mixed effects model using the lme function (nlme library). A sample data is as shown at the bottom of this mail. I fit my linear mixed model using the following R code: bmr <-lme (outcome~ -1 + as.factor(endpoint)+ as.factor(endpoint):trt, data=datt, random=~-1 + as.factor(endpoint) + as.factor(endpoint):trt|as.factor(Trial),

I would like to create a plot of y vs x with different treatments where the points are actually the letter of the treatment. Here is the code: A<-as.matrix(rnorm(10,10)) B<-as.matrix(rnorm(10,9.5)) C<-as.matrix(rnorm(10,10.5)) Y<-as.matrix(rnorm(30,13)) X<-rbind(A,B,C) nA<-matrix("A",10,1) nB<-matrix("B",10,1) nC<-matrix("C",10,1)

Hello, I have a problem with my script. I don'y know how to apply subtitles. I have 9 charts per page (for combination of 3 blocks and 3 treatments). I want to have subtitles for this interaction (e.g. Block A Trt 1, Block A Trt 2, ...) MBE$bt<- interaction(MBE$Block,MBE$trt) par(mfrow=c(3,3)) for(i in unique(MBE$bt)){ ss <- MBE$bt==i plot(MBE$Year[ss], MBE$DBH[ss])

You need to give the model formula that gave your output. There are two sources of variation (at least), within and between locations; though it looks as though your analysis may have tried to account for this (but if so, the terms are not laid out in a way that makes for ready interpretation. The design is such (two locations) that you do not have much of a check that effects are consistent over

#Dear All, #I'm having a bit of a trouble here, please help me... #I have this data set.seed(4) mydata <- data.frame(var = rnorm(100), temp = rnorm(100), subj = as.factor(rep(c(1:10),5)), trt = rep(c("A","B"), 50)) #and this model that fits them lm <- lm(var ~ temp * subj, data = mydata) #i want to