similar to: survreg() with frailty

Hi, I am trying to convert the following NLMIXED code to NLME, but am running into problems concerning 'Singularity in backsolve'. As I am new to R/S-Plus, I thought I may be missing something in the NLME code. NLMIXED *********** proc nlmixed data=kidney.kidney; parms delta=0.03 gamma=1.1 b1=-0.003 b2=-1.2 b3=0.09 b4=0.35 b5=-1.43 varu=0.5; eta=b1*age+b2*sex+b3*gn+b4*an+b5*pkn+u;

Dear R users: I'm generating the following survival data: set.seed(123) n=200 #sample size x=rbinom(n,size=1,prob=.5) #binomial treatment v=rgamma(n,shape=1,scale=1) #gamma frailty w=rweibull(n,shape=1,scale=1) #Weibull deviates b=-log(2) #treatment's slope t=exp( -x*b -log(v) + log(w) ) #failure times c=rep(1,n) #uncensored indicator id=seq(1:n) #individual frailty indicator

I have the following questions about the variance of the random effects in the survreg() function in the survival package: 1) How can I extract the variance of the random effects after fitting a model? For example: set.seed(1007) x <- runif(100) m <- rnorm(10, mean = 1, sd =2) mu <- rep(m, rep(10,10)) test1 <- data.frame(Time = qsurvreg(x, mean = mu, scale= 0.5, distribution =

Hi, I am working with R version 2.1.0, and I seem to have run into what looks like a bug. I get the same error message when I run R on Windows as well as when I run it on Linux. When I call anova to do a LR test from inside a function, I get an error. The same call works outside of a function. It appears to not find the right environment when called from inside a function. I have provided

Dear List, After including cluster() option the coxreg (from eha package) produces results slightly different than that of coxph (from survival) in the following time-dependent treatment effect calculation (example is used just to make the point). Will appreciate any explaination / comment. cheers, Ehsan ############################ require(survival) require(eha) data(heart) # create weights

Dear List, How do I extract the approximate Wald test for the frailty (in the following example 17.89 value)? What about the P-values, other Chisq, DF, se(coef) and se2? How can they be extracted? ######################################################> kfitm1 Call: coxph(formula = Surv(time, status) ~ age + sex + disease + frailty(id, dist = "gauss"), data = kidney)

Dear R users, Could somebody please help me to find a way of comparing nonlinear, non-nested models in R, where the number of parameters is not necessarily different? Here is a sample (growth rates, y, as a function of internal substrate concentration, x): x <- c(0.52, 1.21, 1.45, 1.64, 1.89, 2.14, 2.47, 3.20, 4.47, 5.31, 6.48) y <- c(0.00, 0.35, 0.41, 0.49, 0.58, 0.61, 0.71, 0.83, 0.98,

> I was wondering why survreg (in survival package) can not handle > three-way interactions. I have an AFT ..... You have given us no data to diagnose your problem. What do you mean by "cannot handle" -- does the package print a message "no 3 way interactions", gives wrong answers, your laptop catches on fire when you run it, ....? Also, make sure you read

Dear all, I'm getting an error in one of the stock examples in the 'mvpart' package. I tried: require(mvpart) data(spider) fit3 <- rpart(gdist(spider[,1:12],meth="bray",full=TRUE,sq=TRUE)~water+twigs+reft+herbs+moss+sand,spider,method="dist") #directly from ?rpart summary(fit3) ...which returned the following: Error in apply(formatg(yval, digits - 3), 1,

I try to send this message To Gordon Smyth at smyth at vehi,edu.au but it bounced back, so here it is to r-help I am trying to use limma, just downloaded it from CRAN. I use R 2.0.1 on Win XP see the following: > library(RODBC) > chan1 <- odbcConnectExcel("D:/Data/mgc/Chips/Chips4.xls") > dd <- sqlFetch(chan1,"Raw") # all data 12000 > # > nzw <-

The combination of survreg + gamma frailty = invalid model, i.e., the example that you quote. I did not realize that this had been added to the survreg help file until very recently. I will try to fix the oversight. Other, more detailed documentation states that Gaussian frailty + AIC is the only valid random effects choice for survreg. Details: frailty(x) with no optional

Dear All, I am attempting to make predictions based on a survreg() model with some censoring and a frailty term, as below: predict works fine on the original data, but not if I specify newdata. # a model with groups as fixed effect model1 <- survreg(Surv(y,cens)~ x1 + x2 + groups, dist = "gaussian") # and with groups as a random effect fr <- frailty(groups,

Dear R-Helpers, I am hoping to perform survival analyses using the "ex-Gaussian" distribution. I understand that the ex-Gaussian is a convolution of exponential and Gaussian distributions for survival data. I checked the "survreg.distributions" help and saw that it is possible to mix pre-defined distributions. Am I correct to think that the following code makes the

I am trying to model survival data with a Weibull distribution using survreg. Units are clustered two apiece, sometimes receiving the same treatment and sometimes opposing treatment.

Dear all, Does the frailty.object$history[[1]]$theta returns the Variance of random effect? Why is the value different? Here is an example with kidney data: > library(survival) > data(kidney) > frailty.object<-coxph(Surv(time, status)~ age + sex + disease + frailty(id), kidney) > frailty.object Call: coxph(formula = Surv(time, status) ~ age + sex + disease + frailty(id), data

Folks, I am trying to get a loop to run which increments the object name as part of the loop. Here "fit1" "fit2" "fit3" and "fit4" are linear regression models that I have created. > for (ii in c(1:4)){ + SSE[ii]=rbind(anova(fit[ii])$"Sum Sq") + dfe[ii]=rbind(summary(fit[ii])$df) + } Error in anova(fit[ii]) : object 'fit' not found

Dear List, Can anyone please explain the difference between cluster() and frailty() in a coxph? I am a bit puzzled about it. Would appreciate any useful reference or direction. cheers, Ehsan > marginal.model <- coxph(Surv(time, status) ~ rx + cluster(litter), rats) > frailty.model <- coxph(Surv(time, status) ~ rx + frailty(litter), rats) > marginal.model Call: coxph(formula =

I am confused on how the log-likelihood is calculated in a parametric survival problem with frailty. I see a contradiction in the frailty() help file vs. the source code of frailty.gamma(), frailty.gaussian() and frailty.t(). The function frailty.gaussian() appears to calculate the penalty as the negative log-density of independent Gaussian variables, as one would expect: >

On Tue, 6 May 2003, Jerome Asselin wrote: > > I am confused on how the log-likelihood is calculated in a parametric > survival problem with frailty. I see a contradiction in the frailty() help > file vs. the source code of frailty.gamma(), frailty.gaussian() and > frailty.t(). > > The function frailty.gaussian() appears to calculate the penalty as the > negative

SEE ALSO ORIGINAL POSTING IN PR#2933 On May 6, 2003 03:58 pm, Thomas Lumley wrote: > > Looking at a wider context in the code > > pfun <- function(coef, theta, ndeath) { > if (theta == 0) > list(recenter = 0, penalty = 0, flag = TRUE) > else { > recenter <- log(mean(exp(coef))) > coef <- coef - recenter