similar to: Extracting parameters for Gamma Distribution

Does someone know the rules by which 'coxph' returns 'frail', the predicted frailty terms? In my test function: ----------------------------------------------- fr <- function(){ #testing(frailty terms in 'survival' require(survival) dat <- data.frame(exit = 1:6, event = rep(1, 6), x = rep(c(0, 1), 3),

Hi: I have a few clarification questions about the elements returned by the coxph function used in conjuction with a frailty term. I create the following group variable: group <- NULL group[id<50] <- 1 group[id>=50 & id<100] <- 2 group[id>=100 & id<150] <- 3 group[id>=150 & id<200] <- 4 group[id>=200 & id<250] <- 5 group[id>=250

Dear all, This probably stems from my lack of understanding of the model, but I do not understand the variance of the random effect reported in coxme. Consider the following toy example: #------------------------------- BEGINNING OF CODE ------------------------------------------------ library(survival) library(coxme) #--- Generate toy data: d <- data.frame(id = c(1:100), #

Dear all, I would have some questions on the coxph function for survival analysis, which I use with frailty terms. My model is: mdcox<-coxph(Surv(time,censor)~ gender + age + frailty(area, dist='gauss'), data) I have a very large proportion of censored observations. - If I understand correctly, the function mdcox$frail will return the random effect estimated for each group on the

Dear List, How do I extract the approximate Wald test for the frailty (in the following example 17.89 value)? What about the P-values, other Chisq, DF, se(coef) and se2? How can they be extracted? ######################################################> kfitm1 Call: coxph(formula = Surv(time, status) ~ age + sex + disease + frailty(id, dist = "gauss"), data = kidney)

I have the following questions about the variance of the random effects in the survreg() function in the survival package: 1) How can I extract the variance of the random effects after fitting a model? For example: set.seed(1007) x <- runif(100) m <- rnorm(10, mean = 1, sd =2) mu <- rep(m, rep(10,10)) test1 <- data.frame(Time = qsurvreg(x, mean = mu, scale= 0.5, distribution =

Dear R users, I'm trying to fit a gamma-frailty model on a simulated dataset, with 6 covariates, and I'm running into some results I do not understand. I constructed an example from my simulation code, where I fit a coxph model without frailty (M1) and with frailty (M2) on a number of data samples with a varying degree of heterogeneity (I'm running R 2.3.1, running takes ~1 min).

Hi, I have a question about the output for variance of random effect from a gamma frailty model using coxph in R. Is it the vairance of frailties themselves or variance of log frailties? Thanks. Guanghui

Hi I am estimating the following coxph function with stratification and frailty?where each person had multiple events. m<-coxph(Surv(dtime1,status1)~gender+cage+uplf+strata(enum)+frailty(id),xmodel) ? > head(xmodel) id enum dtime status gender cage uplf 1 1008666 1 2259.1412037 1 MA 0.000 0 2 1008666 2 36.7495023 1 MA 2259.141 0 3 1008666

Dear all, I have a data set<http://yaap.it/paste/c11b9fdcfd68d02b#gIVtLrrme3MaiQd9hHy1zcTjRq7VsVQ8eAZ2fol1lUc=>with 6 clusters, each containing 48 (possibly censored, in which case "event = 0") survival times. The "x" column contains a binary explanatory variable. I try to describe that data with a gamma frailty model as follows: library(survival) mod <-

I get the following error when I try reading in a table. How are 1.1, 1.2, 1.3 duplicate row names? Thx. > table <- read.table('latestWithNumber.txt', header=T) Error in "row.names<-.data.frame"(`*tmp*`, value = c("1.1", "1.2", "1.3", : duplicate 'row.names' are not allowed Yongchuan

Dear R users: I'm generating the following survival data: set.seed(123) n=200 #sample size x=rbinom(n,size=1,prob=.5) #binomial treatment v=rgamma(n,shape=1,scale=1) #gamma frailty w=rweibull(n,shape=1,scale=1) #Weibull deviates b=-log(2) #treatment's slope t=exp( -x*b -log(v) + log(w) ) #failure times c=rep(1,n) #uncensored indicator id=seq(1:n) #individual frailty indicator

Dear all, this is probably a very silly question, but could anyone tell me what the different parameters in a coxph model with a frailty.gamma term mean? Specifically I have two questions: (1) Compared to a "normal" coxph model, it seems that I obtain two standard errors [se(coef) and se2]. What is the difference between those? (2) Again compared to a "normal" coxph model,

Dear R-help, I am trying to estimate a Cox model with nested effects basing on the minimization of the overall AIC; I have two frailties terms, both gamma distributed. There is a error message (theta2 argument misses) and I don?t understand why. I would like to know what I have wrong. Thank you very much for your time. fitM7 <- coxph(Surv(lifespan,censured) ~ south + frailty(id,

I can't comment on frailtypack issues, but would like to mention that coxme will handle nested models, contrary to the statement below that "frailtypack is perhaps the only .... for nested survival data". To reprise the original post's model cgd.nfm <- coxme(Surv(Tstart, Tstop, Status) ~ Treatment + (1 | Center/ID), data=cgd.ag) And a note to the poster-- you should

Dear List, Can anyone please explain the difference between cluster() and frailty() in a coxph? I am a bit puzzled about it. Would appreciate any useful reference or direction. cheers, Ehsan > marginal.model <- coxph(Surv(time, status) ~ rx + cluster(litter), rats) > frailty.model <- coxph(Surv(time, status) ~ rx + frailty(litter), rats) > marginal.model Call: coxph(formula =

Dear all, I'm new to frailty model. I have a question on the output from 'survival' pack. Below is the output. What does gamma1,2,3 refer to? How do I calculate joint hazard function or marginal hazard function using info below? Many thanks! Call: coxph(formula = surv ~ as.factor(tibia) + frailty(as.factor(bdcat)), data = try) n=877 (1 observation deleted due to missingness)

Hello, I am working on the frailty model using coxph functions. I am running some simulations and want to store the variance of frailty (theta) values from each simulation result. Can anyone help me how to extract the theta values from the results. I appreciate any help. Thanks Shankar Viswanathan

Dear List, In documents (Therneau, 2003 : On mixed-effect cox models, ...), as far as I came to know, coxme penalize the partial likelihood (Ripatti, Palmgren, 2000) where as frailtyPenal (in frailtypack package) uses the penalized the full likelihood approach (Rondeau et al, 2003). How, then, coxme and coxph(...frailty(id, dist='gauss')) differs? Just the coding algorithm, or in

Hi, I am trying to convert the following NLMIXED code to NLME, but am running into problems concerning 'Singularity in backsolve'. As I am new to R/S-Plus, I thought I may be missing something in the NLME code. NLMIXED *********** proc nlmixed data=kidney.kidney; parms delta=0.03 gamma=1.1 b1=-0.003 b2=-1.2 b3=0.09 b4=0.35 b5=-1.43 varu=0.5; eta=b1*age+b2*sex+b3*gn+b4*an+b5*pkn+u;