similar to: Reshaping genetic data from long to wide

I am using dgc.genetics to perform TDT analysis on SNP data from a cohort of trios. I now have a file with about 6008 variables. The first few variables related to the pedigree data such as the pedigree ID the person ID etc. Thereafter each variable is a specific locus or marker. The variables are named by a pattern such as "Genotype.nnnnn" with nnnnn corresponding to a number which

I a using plink on a large SNP dataset with a .map and .ped file. I want to get some sort of file say a list of all the SNPs that plink is saying that I have. ANyideas on how to do this? -- Thanks, Jim. [[alternative HTML version deleted]]

A while back Gabor Grothendieck suggested that I try http://news.gmane.org/gmane.comp.lang.r.general. This was after I asked how to easily reply to posts on the listserve. Ideally I would like the functionality that I find in Microsoft Outlook Express newsreader for usenet groups or what I find in Google Groups. I started using gmane about 3 weeks ago. I find it fantastic for searching and for

I am about one step away from heaven on earth. I think only one step! I am using dgc.genetics to run a TDT test on thousands of genetic loci. I have learnt (through the help of others on this mailing list) to send the complex output to useful data frames which in turn allow me to look at the big picture and screen the thousands of loci. Resultdt<-lapply(PGWide[,240:290], tdt) the above

snpMatrix package is quite nice (read.plink())

I am in R command window and just make Crt+V. Corinna -----Ursprüngliche Nachricht----- Von: Farrel Buchinsky [mailto:fbuchins@wpahs.org] Gesendet: Mo 11.02.2008 21:16 An: Schmitt, Corinna Betreff: Re: Tinn-R not working well with latest R I can easily get R to open without an error. I simply removed the Tinn-R related lines from the Rprofile.site file C:\Program

Power calculations two sample test for proportions is very useful. Is there a way however, to get away from the two samples being of the same size. What would happen if one had n=15 in the one sample and n=45 in the other sample. Farrel Buchinsky, MD Pediatric Otolaryngologist Allegheny General Hospital Pittsburgh, PA **********************************************************************

Hi Mr Tierney, I have noticed an error message from R 1.12.x's CMD check for a while (apparently prof Ripley completely rewrote CMD check in R 1.12+) e.g.: http://bioconductor.org/checkResults/2.7/bioc-LATEST/snpMatrix/lamb2-checksrc.html ---------------- * checking R code for possible problems ... NOTE Warning: non-unique value when setting 'row.names': ?new? Error in

I am involved in a study where, as in most of life, men demonstrate themselves to be recalcitrant. So while we have many probands and most of their mothers we only have about 50% of the trios being complete. I have been running tdt and trio.types. It appears as if it is ignoring the duos. Sometimes a duo can be informative. For instance Father ..missing Mother 1/2 Proband 1/1 This duo shows that

I have hundreds of humans who have undergone SNP genotyping at hundreds of loci. Some have even undergone the procedure twice or thrice (kind of an internal control). So obviously I need to find those replications, and confirm that the results are the same. If there is discordance then I need to address it. I tried to use the aggregate function nr.attempts

I installed the newest version of R and once again ran into problem with Tinn-R failing when trying to use the R explorer. I had this problem once before and solved it when I added the following .trPaths = c( 'C:/Documents and Settings/fbuchins/Application Data/Tinn-R/tmp/', 'C:/Documents and Settings/fbuchins/Application Data/Tinn-R/tmp/search.txt', 'C:/Documents and

Dear All, Does anybody have experience with R package pbatR (http://cran.r-project.org/web/packages/pbatR/index.html)? I am trying to use it to analyze the family-based case-control data, but the package totally doesn?t work on my computer. I contacted the authors of the package, but I haven?t heard anything from them. Following the package manual, I tried the simple example as below:

Has something changed in R that requires an update in the genetics package by Gregory Warnes? I am using R version 2.5.0 This used to work > summary(founders[,59]) to prove that it is a genotype class > class(founders[,59]) [1] "genotype" "factor" Now when I issue the command: > summary(founders[,59]) I get: Error in attr(retval, "which") <- which :

#Hello, #I have a question about obtaining results from a loop I have written. #Below is a sample of individual genotypes from a genetic question I am working on called "P.genotype.sample ". P.genotype.sample<-matrix(10,10,10) P.genotype.sample[,1]<-c(2,2,1,5,1,1,5,6,1,3) P.genotype.sample[,2]<-c(6,3,3,6,8,1,6,7,2,3) P.genotype.sample[,3]<-c(2,2,2,3,3,2,2,2,3,3)

Hello, I am building a R-package for Genetics analysis. The accepted data is in pedigree (.ped) file format. To load the data (say CAMP.ped) from "data" directory, I have a function "CAMP.R", which does the job. The package builds successfully in Linux (.tar.gz) and the data loads successfully by "data(CAMP)". However, when I build the package in WINDOWS, the data

Hi, Following my earlier posts about having problems performing a PCA, I have worked out what the problem is. The problem lies within the PLINK to gds conversion. It seems as though the SNPs are imported as "samples" and in turn, the samples are recognised as SNPs: >snpsgdsSummary("chr2L") Some values of snp.position are invalid (should be > 0)! Some values of

Hello, I did a pca with over 200000 snps for 340 observations (ids). If I plot the eigenvectors (called rotation in prcomp) 2,3 and 4 (e.g. plot (rotation[,2]) I see a strange "column" in my data (see attachment). I suggest it is an artefact (but of what?). Suggestion: I used prcomp this way: prcomp (mat), where mat is a matrix with the column means already substracted followed by a

Hi all, We are using two methods to identify SNPs. One is based on resequencing the genome and aligning the reads to the sequenced genome to identify SNPs (data available for 44 individuals). Another is based on SNP array with selected loci (30000 loci, 870 individuals). I want to compare the results from the resequencing based minor allele frequency and Array based minor allele frequency.

Hi All, I have a problem with weighted logistic regression. I have a number of SNPs and a case/control scenario, but not all genotypes are as "guaranteed" as others, so I am using weights to downsample the importance of individuals whose genotype has been heavily "inferred". My data is quite big, but with a dummy example: > status <- c(1,1,1,0,0) > SNPs <-

Hi, I have a genotype data for both case and controls and would like to calculate the HW p-value. However, since the number of one genotype is 0, I got wired result. Would someone help me to figure it out? Or confirm it's right? Thanks a lot. ============ > library( "genetics" ) NOTE: THIS PACKAGE IS NOW OBSOLETE. The R-Genetics project has developed an set of enhanced