similar to: p-values for classification

You asked the same question on the Bioconductor mailing list back in August. At that time, you suggested yourself a solution for how the adjusted p-values should be interpreted. I answered your query and told you that your interpretation was correct. So I'm not sure what more can be said, except that you should read the article Wright (1992), which is cited in the help entry for p.adjust(),

Dear R-Help, I am using the function "topTable" from the LIMMA package. To estimate adjusted P-values there are several options (adjust="fdr" , adjust="BH") as shown below: topTable(fit, number = 10, adjust = "BH", fit$Name) I guess any of these options (fdr, BH, etc.) is using a default of FDR=0.05 which is quite conservative (i.e., very

I am getting the following error in my script. I am very very new to R and have obtained this script from another person. #read file in (dummy data) starburst.plot<-function(affy.fold, affy.FDR)(ifelse( ((affy.fold) >=0), -1*log10(affy.FDR), 1*log10(affy.FDR))) starburst.plot<-function(meth.fold, meth.FDR)(ifelse( ((meth.fold) >=0), -1*log10(meth.FDR), 1*log10(affy.FDR))) At my next

Dear R-people! I??m trying to write a C program that write to the standard input of R and read the standard output. I can perfectly read the R output, but I??m not able of writing anything to R. This program really works with the 'cat?? UNIX command, but it does not work with R. What I??m doing wrong??? It is possible to do it??? I want to start R once and use it thousands of times...

Dear R-people! I??m trying to write a C program that write to the standard input of R and read the standard output. I can perfectly read the R output, but I??m not able of writing anything to R. This program really works with the 'cat?? UNIX command, but it does not work with R. What I??m doing wrong??? It is possible to do it??? I want to start R once and use it thousands of times...

I try to send this message To Gordon Smyth at smyth at vehi,edu.au but it bounced back, so here it is to r-help I am trying to use limma, just downloaded it from CRAN. I use R 2.0.1 on Win XP see the following: > library(RODBC) > chan1 <- odbcConnectExcel("D:/Data/mgc/Chips/Chips4.xls") > dd <- sqlFetch(chan1,"Raw") # all data 12000 > # > nzw <-

Dear All, It is not a typical R question (though I use R for this) but I thought someone will help me. For the list of P values, I have calculated FDR using p.adjust() in R (bioconductor). But my FDR values are same for all the P values. When do we get same FDR values? Does the smallest P values should less than 1/N? (where N is the number of P values) Thanks in advance. Kind regards, Ezhil

Hello, I've a question about the fdr method in p.adjust: What is the threshold of the FDR, and is it possible to change this threshold? As I understand the FDR (please correct) it adjusts the p-values so that for less than N% (say the cutoff is 25%) of the alternative hypothesis the Null is in fact true. thanks a lot for help, +regards, Arne

I have developed a problem with the postscript output of plot on Windows. My code still works properly with R 2.3 but, with R 2.4, the white text on red background does not show up. It does, however, show up when output is sent to the screen. Below is my code and sessionInfo. R version 2.4.0 Under development (unstable) (2006-08-29 r39012) i386-pc-mingw32 locale: LC_COLLATE=English_United

The Partek package (www.partek.com) allows only two selections for Multiple Test Correction: Bonferroni and Dunn-Sidak. Can anyone suggest why Partek implemented Dunn-Sidak and not the other methods that R has? Is there any particular advantage to the Dunn-Sidak method? R knows about these methods (in R 2.1.1): > p.adjust.methods [1] "holm" "hochberg" "hommel"

Dear R users, I am wondering about the following results: > p.adjust(c(0.05,0.05,0.05),"fdr") [1] 0.05 0.05 0.05 > p.adjust(c(0.05,0.04,0.03),"fdr") [1] 0.05 0.05 0.05 Why does p.adjust(..., "fdr") not adjust p-values, if they are constant? Does somebody have an explanation or can point to a reference? Thanks in advance, Will

> Note that "stripe" is not tested much and practically unmaintained. Ah, this was what I suspected. Understood. I'll be happy with "shard". Having said that, "stripe" works fine with transport=tcp. The failure reproduces with just 2 RDMA servers (with InfiniBand), one of those acts also as a client. I looked into logs. I paste lengthy logs below with

On Wed, Aug 16, 2017 at 4:44 PM, Hatazaki, Takao <takao.hatazaki at hpe.com> wrote: >> Note that "stripe" is not tested much and practically unmaintained. > > Ah, this was what I suspected. Understood. I'll be happy with "shard". > > Having said that, "stripe" works fine with transport=tcp. The failure reproduces with just 2 RDMA servers

I am posting this to both R and BioC communities because I believe there is a lot of confusion on this topic in both communities (having searched the mail archives of both) and I am hoping that someone will have information that can be shared with both communities. I have seen countless questions on the BioC list regarding limma (Bioconductor) and its calculation of FDR. Some of them involved

I am posting this to both R and BioC communities because I believe there is a lot of confusion on this topic in both communities (having searched the mail archives of both) and I am hoping that someone will have information that can be shared with both communities. I have seen countless questions on the BioC list regarding limma (Bioconductor) and its calculation of FDR. Some of them involved

Dear All: Significance Analysis of Microarrays(SAM) As we know sam do multiple t.test as following ## Default S3 method: t.test(x, y = NULL, alternative = c("two.sided", "less", "greater"),mu = 0, paired = FALSE, var.equal = FALSE,conf.level = 0.95, ...) var.equal: a logical variable indicating whether to treat the two variances as being equal. If 'TRUE'

I am using Efron's local fdr procedure. But, I want to change the null from N(0,1) to N(0, 0.002). I can access the function but I have no idea what to change. In other words, I want nulltype to be N(0,0.002) instead of N(0,1) in his function. Anyone has any ideas. This is his code for the local fdr: function (zz, bre = 120, df = 7, pct = 0, pct0 = 1/4, nulltype = 1, type = 0, plot = 1,

Hello, I am not sure about the p.adjust( , fdr). How do these adjusted p-values get? I have read papers of BH method. For independent case, we compare the ordered p-values with the alfa*i/m, where m is the number of tests. But I have checked that result based on the adjusted p-values is different with that by using the independent case method. Then how do the result of p.adjust( , fdr) come? And

# Objective Implement an XRay mode 'xray-profiling' that gathers stack trace latencies/durations and builds histograms to provide basic statistics about where time is going in an execution of the application. # Background XRay has two modes currently implemented in compiler-rt: a basic (nee naive) mode and flight data recorder (FDR) mode. Basic mode logging, when enabled, will collect

Hola a todos, Tengo un pequeño problemilla... Tengo unas 9000 variables que he contrastado con 1 en concreto con el test de wilcoxon. He calculado el p-valor, y queria corregirlo con el permutation-based FDR. He encontrado una funcion con R comp.fdr()que hace esta corrección, pero te pide que le pongas las variables con las observaciones y te hace el test (según he entendido). Yo solo quiero