similar to: R package hypred: Simulation of genomic data in applied genetics

Dear Frank, I hope everything is well with you. ? ?First of all? ?, I? ?'d like thank you for your nice genomic simulation program (*hypred *package) and also for taking your time to answer my question. Dear Frank, I'm a PhD student of animal breeding science from Iran. Unfortunately although I try more time for running your package in order to simulate of a historical and reference

Hello Lady or Sir, I want to do model selection with 'step' function. But there is a trouble to me. For example, there are 5 independent variables, X0,X1,X2,X3 and X4; and 1 dependent variable y. I want to run stepwise regression y ~ X0 + X1 + X2 + X3 + X4, and I want to keep X0 always in the model. Every time when I run command 'step' with 'keep', error information

Dear all, I'm looking for a way to solve a simple optimization problem with a nonlinear constraint. An example would be max x s.t. y = x * T ^(x-1) where y and T are known values. optim() and constrOptim() do only allow for box or linear constraints, so I did not succedd here. I also found hints to donlp2 but this does not seem to be available anymore. Any hints are welcome,

Our group in the Biostatistics Department at the University of Washington is currently seeking a data analyst to work on projects with genetic data. Our computing environment is almost exclusively R and we have developed several R and BioConductor packages. Position Description: The Department of Biostatistics of the University of Washington, through the Center for Biomedical Statistics and the

Dear all, I'm looking for a way to replace NA's with 0 for a number of variables which share the same ending and which constitute a subset of a data frame. Say, for example, there is > data <- data.frame(ax=c(1,2,3,NA,0) , bx=c(3,5,NA,5,1) , ay=c(5,NA,2,NA,0) , by=c(4,2,NA,2,1)) > data ax bx ay by 1 1 3 5 4 2 2 5 NA 2 3 3 NA 2 NA 4 NA 5 NA 2 5 0 1 0 1 I wish

Dear Helpers, I have a dataset X, with no missing values, everything is in order, R reads it correctly, and I have already done some statistical analyses on the dataset. The data are in order by date (six sampling dates in one year, earliest to latest) and I now want to generate boxplots for each parameter for each date. However, R outputs the boxplots in some order that I do not understand (eg.

Dear all, we seek a talented and motivated post-doc to develop computational methods for inferring the molecular basis of genetic diseases by integration of personal omics data. Research topics include: identifying causal mutations of rare disease patients by meta-analysis; inferring disease-causing molecular pathways from genotype, phenotypes, and omics profile of patient-derived cell lines

Hi, this is my first time using R. I want to simulate the following process: "in a population of size N, there are i individuals bearing genotype A, the number of those bearing A is j in the next generation, which following a binominal distribution (choose j from 2*N, the p is i/2*N), to plot the probability of the next generations, my script is as follows. It cannot run successfully,

Hi, is there any package/function in Bioconductor that can do this: if given the chromosome positions of a fragment, find out all genes within, and with the information about which strand is the sense strand. And vice versa. Thanks a lot. ----- Appreciate your time & attention! -- View this message in context: http://www.nabble.com/list-genes-w-n-a-genomic-fragment-tp18331452p18331452.html

Genome Institute of Singapore (GIS) Biostatistics Group The Genome Institute of Singapore ( http://www.gis.a-star.edu.sg <http://www.gis.a-star.edu.sg> ) is looking for statisticians who are interested in a wide range of biomedical probems. We are especially interested in hearing from senior researchers interested in leading their own group. The institute is well-funded and engaged

Great R people, I have noticed a strange behaviour in read.delim() and friends in the R 2.7.0 version. I will describe you the problem and also the solution I already found, just to be sure it is an expected behaviour and also to tell people, who may experience the same difficulty, a way to overcome it. And also to see if it is a proper behaviour or maybe a correction is needed. Here is the

Hello to everyone! I have built CRAN task view for genetics. For now I have not submit it to CRAN yet and it can be accessible from: http://www.bfro.uni-lj.si/MR/ggorjan/software/R/Genetics.html http://www.bfro.uni-lj.si/MR/ggorjan/software/R/Genetics.ctv I have not submitted it to CRAN, since I would like first some opinion about it. Genetics is really so broad field that I belive one person

Please do NOT contact me for this post. Please see below for contact details. The company offers solutions for the secure storage and analysis of patient genome sequence information to enable its effective, confidential application to personalized healthcare. The jobholder will be involved in clinical next generation sequence (NGS) data analysis pipeline development. The candidates will be

I am aware of the R Genetics Project that developed the R library and software called Bioconductor (http://www.bioconductor.org/ ) . How do the two relate to each other? What is the one that the other is not and vice versa? Can anybody link me to something that answers the question? -- Farrel Buchinsky, MD Pediatric Otolaryngologist Allegheny General Hospital Pittsburgh, PA

Hello, I've downloaded the metadata plugin from http://hg.intevation.org/kolab/dovecot-metadata-plugin compiled it without errors, made the entries as described in README in dovecot.conf. Only ANNOTATEMORE or anything else additional doesn't show up in the capabilties. Is there anything wrong with my configuration? What I see is: telnet localhost 143 Trying 127.0.0.1... Connected to

Hello All The third virtual conference on genomics and bioinformatics will host by North Dakota State University September 16-19, 2003 More details http://www.ndsu.edu/virtual-genomics/conference_2003.htm Call for papers and 2002 accepted papers http://www.ndsu.edu/virtual-genomics/papers_2003.htm Third Virtual Conference on Genomics and Bioinformatics: September 16-19, 2003 Advances in

Dear Sir, We need to use genetics packages at our end. We have installed R packages. When i try to choose genetics package and install, it is giving an error. Please see the attachment for the error. How can i resolve it and make it work? Thanking you A Padmavathi Devi Technical Officer Centre for Cellular and Molecular Biology Ph.No:27192776 "The person addressed in the email is the sole

Dear friends - a couple of papers in PNAS (lastly:framework for making better predictions by directly estimating variables' predictivity, Lo et al PNAS 2016; 113:14277-14282) have focused interest on mapping complex traits to multiple loci spread all over the genome. I have been around on the relevant taskview(s) I hope but fail to see that the backward haplotype transmission association

The "genetics" package for handling single-locus genetic data is now available on CRAN in both source and Windows binary formats. The purpose of this package is to make it easy to create and manipulate genetic information, and to facility use of this information in statistical models. The library includes classes and methods for creating, representing, and manipulating genotypes

The "genetics" package for handling single-locus genetic data is now available on CRAN in both source and Windows binary formats. The purpose of this package is to make it easy to create and manipulate genetic information, and to facility use of this information in statistical models. The library includes classes and methods for creating, representing, and manipulating genotypes