similar to: non-linear regression and root finding

? Mon, 6 Nov 2023 17:53:49 +0100 Troels Ring <tring at gvdnet.dk> ?????: > Hence I wonder if I could somehow have non linear regression to find > the 3 pK values. Below is HEPESFUNC which delivers charge in the > fluid for known pKs, HEPTOT and SID. Is it possible to have > root-finding in the formula with nls? Sure. Just reformulate the problem in terms of a function that

Thanks a lot! This was amazing. I'm not sure I see how the conditiion pK1 < pK2 < pK3 is enforced? - it comes from the derivation via generalized Henderson-Hasselbalch but perhaps it is not really necessary. Anyway, the use of Vectorize did the trick! Best wishes Troels Den 06-11-2023 kl. 19:19 skrev Ivan Krylov: > ? Mon, 6 Nov 2023 17:53:49 +0100 > Troels Ring <tring at

I won't send to list, but just to the two of you, as I don't have anything to add at this time. However, I'm wondering if this approach is worth writing up, at least as a vignette or blog post. It does need a shorter example and some explanation of the "why" and some testing perhaps. If there's interest, I'll be happy to join in. And my own posting suggests how the

Thanks a lot, Berwin. Unfortunately, pK1 may well be negative and as I understand the literature it may be poorly defined as such, and also seems to be at a boundary, since when lower is set to say rep(-4,3) pK1 is returned as -4 while pK2 and pK3 are undisturbed. Perhaps the point is that pK1 is not carrying any information at the pH around 5. Fair enough, I guess. Only, I believe I need

G'day Troels, On Mon, 6 Nov 2023 20:43:10 +0100 Troels Ring <tring at gvdnet.dk> wrote: > Thanks a lot! This was amazing. I'm not sure I see how the conditiion > pK1 < pK2 < pK3 is enforced? One way of enforcing such constraints (well, in finite computer arithemtic only "<=" can be enforced) is to rewrite the parameters as: pK1 = exp(theta1) ##

Dear R-helpers ? I have 7 data points that I want to fit a continuous curve to, that should look similar to a sine wave My data points would mark the local minima and maxima respectively. This is what I?ve got so far. And I would keep doing so, but sadly nls() then says that it has reached the maximum number of Iterations? ?

Hi, I apologize for the long message but the problem I encountered can't be stated in a few lines. I am having some problems with the function constrOptim. My goal is to maximize the likelihood of product of K multinomials, each with four catagories under linear constraints on the parameter values. I have found that the function does not work for many data configurations. #The likelihood

In one package (pk1) I define some S3 generics and methods. In pk2 I extend the methods to some S4 objects following the description in ?Methods, with setMethod() and setGeneric() either explicit or implicit (tried both). I export the S3 generic and methods from pk1 NAMESPACE and the S4 from pk2. This works, except when I try to use a function defined in pk1, Within the function the S4 method

Hi all Just a quick thanks first for all the efforts that go into such a rewarding piece of kit. Well done Wine and all behind it. Now.....I'm not a big gamer, however, I wanted something different to civ4 and browsed your platinum games and found Call of Duty....next step Amazon.....2days later I try to play it. I have Ubuntu 8.10 and wine 1.1.10 The game installed but when I run it I

I have a small table that is used to temporarily queue requests, as such it does not have an id field (or any other primary key), because it doesn''t make sense to have one. When I created an ActiveRecord class and tried to save it, I get: ActiveRecord::StatementInvalid: PGError: ERROR: relation "temp_requests_id_seq" does not exist It keeps looking for the id to auto

Hi, Since the installation of R-2.3.0 I have the following problems: 1. Startup .First() produces ------------------ Started in /home/woodstock/hoffmann/Projects/RtoZ/Windwurf/R with '~/R/.Rprofile' edited on 2006-04-28, 11:08 During startup - Warning messages: 1: use of NULL environment is deprecated 2: use of NULL environment is deprecated 3: use of NULL environment is

hi guys, plz help... i am trying to play American McGee's Alice(tm) (its from 2000), and i installed it. but when i try to run it i get: Code: American McGee's Alice win-x86 Nov 13 2000 ----- FS_Startup ----- Current search path: Z:\media\Windows\Games\Ububntu\Alice (2000)\base\pak4_english.pk3 (44 files) Z:\media\Windows\Games\Ububntu\Alice (2000)\base\pak3.pk3 (9 files)

Hi, WINE 1.2.2, Return to Castle Wolfenstein retail patched to 1.4.1, OS X 10.6.6, Mac Pro 2010 with ATI 5770. The error message is as stated in the title. According to a post here: > Newer AMD and NVIDIA drivers have so many OpenGL Extensions that Quake 3 engine based games crash when probing the extensions at game launch. > > 2 solutions: > > Download these fixed binaries

Hello Everybody! :D :D :D I changed from Windows to Ubuntu a short time ago. Under Win I programmed microcontrollers with Microchip PicKit2 programmer, which has USB connection. After I installed Ms .NET Framework 2.0 with winetricks, the Wine enablet do install PicKit2 program; it runs, but can not wiev / handle programmer, which I plug in to an USB port. Please help me. Have any USB

Hi, Does anyone know if the D'agostino test is available with R ? Alex

How can i disable the auto-increment for a primary key data type. The purpose of using primary_key data type is using different name for primary key. But we still want to use all the properties of "id" except for auto increment part. I had my migration as following #=============MIGRATION def self.up create_table :pk2s , :id=> false do |t| t.primary_key :uid

-----BEGIN PGP SIGNED MESSAGE----- Hash: SHA1 Hi List, in ldapsearch you are able to use paging in case of limited results on ldap server side with "-E pr=10000/noprompt" Is there any way to get the same effect for the iterate query? Thanks Andre -----BEGIN PGP SIGNATURE----- Version: GnuPG v2.0.22 (GNU/Linux) iQEcBAEBAgAGBQJWWHvwAAoJEAoTNwRDnEhRVmMH/0+vGRx7urQ49bHbzc4asD7r

http://bugzilla.mindrot.org/show_bug.cgi?id=533 Summary: sshd failure on Tru64 (OSF/1) 5.1a Product: Portable OpenSSH Version: 3.6p1 Platform: Alpha OS/Version: OSF/1 Status: NEW Severity: critical Priority: P2 Component: sshd AssignedTo: openssh-unix-dev at mindrot.org ReportedBy:

I have two tables: Table [packages] id name user_name ------------------- 1 PK1 Ray ------------------- Table [users] id name full_name ------------------- 2 Ray Ray Sun ------------------- My purpose is to find the full name when I find packages. So I modify Model Package to: class Package < ActiveRecord::Base belongs_to :user, :class_name => "User",

Hello list. I'm trying to rebuild the 2.6.9.67.0.20.EL kernel, but it fails even without modifications. How did I try it? Created a (non-root) build environment (not a mock ) Installed the kernel.scr.rpm and did a rpmbuild -ba --target=`uname -m` kernel-2.6.spec 2> prep-err.log | tee prep-out.log The build failed at the end: Processing files: kernel-xenU-devel-2.6.9-67.0.20.EL Checking