Displaying 20 results from an estimated 1000 matches similar to: "Correcting for overdispersion"
2014 Mar 17
5
LD50
Quiero comparar varias dosis letales 50% (LD50) usando análisis probit. He
seguido un ejemplo que viene en paquete DRC, pero no obtengo el resultado
esperado. Lo que quiero es saber si las LD50s, son diferentes y si la
diferencias son estadísticamente significativas.
Gracias de antemano.
José Arturo
e-mail. jafarfan@uady.mx <grejon@uady.mx>
e-mail alterno. jafarfan@gmail.com
2002 Mar 21
2
Small typo in An Introduction to R (PR#1402)
At a snail's pace I keep on translating an introduction to R into italian;
I have reached the section describing the glm() function, in which some
example code is presented. The very last line of code, before the
beginning of the section on Poisson models is:
ldp <- ld50(coef(fmp)); ldl <- ld50(coef(fmp)); c(ldp, ldl)
which of course gives results 43.663 and 43.663; the correct code
2002 Mar 21
2
Small typo in An Introduction to R (PR#1402)
At a snail's pace I keep on translating an introduction to R into italian;
I have reached the section describing the glm() function, in which some
example code is presented. The very last line of code, before the
beginning of the section on Poisson models is:
ldp <- ld50(coef(fmp)); ldl <- ld50(coef(fmp)); c(ldp, ldl)
which of course gives results 43.663 and 43.663; the correct code
2008 Feb 12
1
Finding LD50 from an interaction Generalised Linear model
Hi,
I have recently been attempting to find the LD50 from two predicted fits
(For male and females) in a Generalised linear model which models the effect
of both sex + logdose (and sex*logdose interaction) on proportion survival
(formula = y ~ ldose * sex, family = "binomial", data = dat (y is the
survival data)). I can obtain the LD50 for females using the dose.p()
command in the MASS
2009 Mar 22
1
Estimating LC50 from a Weibull distribution
I am attempting to estimate LC50 (analogous to LD50, but uses exposure
concentration rather than dose) by fitting a Weibull model; but I
can't seem to get it to work. From what I can gather, I should be
using survreg() from the survival package. The survreg() function
relies on time-to-event data; my data result from 96 h exposures
(i.e., dead or alive after a fixed period; 96 h). I've
2006 Nov 22
1
Probit analysis
Respected Sir/Madam,
I have a question regarding calculation of LD50 (Lethal Dose) and IC50 (50%
inhibitory concentration) of an antimicrobial experiment.
I have used a compound isolated from a plant and observed its effect on the
fungus *Fusarium oxysporum* by the food poisoning method. Solutions of the
compound at concentrations of 0, 50, 100, 150, 200 and 250µg/ ml were added
to
2006 Aug 21
1
Fwd: Re: Finney's fiducial confidence intervals of LD50
thanks a lot Renaud.
but i was interested in Finney's fiducial confidence intervals of LD50 so to obtain comparable results with SPSS.
But your reply leads me to the next question: does anybody know what is the best method (asymptotic, bootstrap etc.) for calculating confidence intervals of LD50?
i could "get rid" of Finney's fiducial confidence intervals but
2010 Jan 07
1
LD50 and SE in GLMM (lmer)
Hi All!
I am desperately needing some help figuring out how to calculate LD50 with a GLMM (probit link) or, more importantly, the standard error of the LD50.
I conducted a cold temperature experiment and am trying to assess after how long 50% of the insects had died (I had 3 different instars (non significant fixed effect) and several different blocks (I did 4 replicates at a time)=
2002 Jul 16
3
dose.p in MASS
Dear all
I need to obtain an estimate of the 50% lethal dose (LD50) from a
logistic regression model obtained by applying the glm procedure to
some binomial data. The model appears to fit the data very well. I
used dope.p from MASS to try and find LD50.
The following output appears:
> dose.p(iso.glm.logit, cf = c(1,3), p = 1:3/4)
Error in dose.p(iso.glm.logit, cf = c(1, 3), p = 1:3/4) :
2010 Nov 22
2
Probit Analysis: Confidence Interval for the LD50 using Fieller's and Heterogeneity (UNCLASSIFIED)
Classification: UNCLASSIFIED
Caveats: NONE
A similar question has been posted in the past but never answered. My
question is this: for probit analysis, how do you program a 95%
confidence interval for the LD50 (or LC50, ec50, etc.), including a
heterogeneity factor as written about in "Probit Analysis" by
Finney(1971)? The heterogeneity factor comes into play through the
chi-squared
2006 Aug 21
2
Finney's fiducial confidence intervals of LD50
I am working with Probit regression (I cannot switch to logit) can anybody help me in finding out how to obtain with R Finney's fiducial confidence intervals for the levels of the predictor (Dose) needed to produce a proportion of 50% of responses(LD50, ED50 etc.)?
If the Pearson chi-square goodness-of-fit test is significant (by default), a heterogeneity factor should be used to calculate
2007 Jul 12
1
dose-response on a grid
I have the following problem. I have measured a dose response curve
(binary response, continuous dose) on a grid of x,y positions. I would
like to produce a grey-level plot that shows the LD50 at each (x,y)
position.
I am thinking that I have to do something like
fit<-glm(resp ~ x*y + dose, family = binomial)
Corrections welcome.
But from here I don't know how to get LD50, and certainly
2000 Oct 27
1
- Estimate LD50 with bnlr{gnlm}
Hi,
I'm not yet familar with GLM and still learning.
How can I perform a BNL (to estimate LDp values) with matrixes like this
(N indicates the observed objects):
data from:
Kerr D, Meador J. 1996. "Modeling Dose Response Using Generalized Linear
Models". Environ Toxicol Chem 15(3)
conc respond n
0 0 20
0 1 19
0 1 20
0 0 20
13.5 5 23
13.5 2 20
29 9 20
29 6 20
53 12 20
53 15 20
85
2012 Jun 20
1
Problem with predict?
Hello,
I am trying to fit a model to some "death over time" data that does not fit the criteria for the usual LD50 type models (the counts are too large). I am using a simple linear model in an attempt to plot a nice line on a scatter plot and calculate some LD values to use in designing an experiment. Here is the basic idea of what I'm doing:
head(mort)
Time Density
0
2002 Mar 07
1
R 1.5.0 scheduled for April 29th, feature freeze April 8
The core team has decided to release R 1.5.0 on April 29th. Somewhat
earlier than maybe expected, but we realized that we needed a
phase-shift away from our usual cycle with main releases in June and
December since it was placing feature freezes just when several
members were in a creative phase due to end of teaching.
The roadmap is as follows
April 8 feature freeze on r-base
April 15 code
2011 Apr 01
1
qcc.overdispersion-test
Hi all,
I have made an overdispersion test for a data set and get the following result
Overdispersion test Obs.Var/Theor.Var Statistic p-value
poisson data 16.24267 47444.85 0
after deleting the outliers from the data set I get the following result
Overdispersion test Obs.Var/Theor.Var Statistic p-value
poisson data 16.27106 0 1
The
2008 Feb 11
1
overdispersion + GAM
Hi,
there are a lot of messages dealing with overdispersion, but I couldn't find
anything about how to test for overdispersion. I applied a GAM with binomial
distribution on my presence/absence data, and would like to check for
overdispersion. Does anyone know the command?
Many thanks,
Anna
--
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2007 Jan 11
2
overdispersion
How can I eliminate the overdispersion for binary data apart the use of the quasibinomial?
help me
Eva Iannario
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2008 Apr 21
1
estimate of overdispersion with glm.nb
Dear R users,
I am trying to fully understand the difference between estimating
overdispersion with glm.nb() from MASS compared to glm(..., family =
quasipoisson).
It seems that (i) the coefficient estimates are different and also (ii) the
summary() method for glm.nb suggests that overdispersion is taken to be one:
"Dispersion parameter for Negative Binomial(0.9695) family taken to be
2012 Oct 18
2
Assessing overdispersion and using quasi model with lmer, possible?
Hello!
I am trying to model data on species abundance (count data) with a poisson
error distribution. I have a fixed and a random variables and thus needs a
mixed model. I strongly doubt that my model is overdispersed but I don't
know how to get the overdispersion parameter in a mixed model. Maybe someone
can help me on this point. Secondly, it seems that quasi models cannot be
implemented