similar to: FlexMix for clustering of gene expression data

Displaying 20 results from an estimated 20000 matches similar to: "FlexMix for clustering of gene expression data"

2009 Nov 09
1
model based clustering with flexmix
Hello all, I am trying to fit a truncated mixture model and I wrote a driver for flexmix following the example in the vignette, but it doesn't work for me: it assigns all data points to one component only, e.g.: > > source('bugged.R') > > Call: > flexmix(formula = x ~ 1, k = 2, model = truncatedmodel(lower = -4, > upper = 4)) > > prior size
2004 Oct 19
0
flexmix version 1.0-0 released
Dear useRs, FlexMix version 1.0-0 has been released on CRAN. FlexMix implements a general framework for finite mixtures of regression models using the EM algorithm. FlexMix provides the E-step and all data handling, while the M-step can be supplied by the user to easily define new models. Existing drivers implement mixtures of standard linear models, generalized linear models and model-based
2004 Oct 19
0
flexmix version 1.0-0 released
Dear useRs, FlexMix version 1.0-0 has been released on CRAN. FlexMix implements a general framework for finite mixtures of regression models using the EM algorithm. FlexMix provides the E-step and all data handling, while the M-step can be supplied by the user to easily define new models. Existing drivers implement mixtures of standard linear models, generalized linear models and model-based
2011 Jan 12
0
flexmix: predictions on new data from flexmix object
Dear R Users, R Core Team, I currently wonder how to predict the probability of an event with new data resulting from a finite mixture. I read the documentation of the flexmix package and the examples of applications provided on CRAN but I could not find how to predict (except "manually" but I am looking for a simpler solution) the final probability of the mixture (for each individual)
2009 Dec 04
0
flexmix and mclust help
Hello, I'm trying out flexmix and mclust for the first time on some univariate data which is typically best described as lognormal, but can sometimes be gamma distributed as well. I first tried using EM on mclust assuming the data was lognormally distributed and could only get it to work in "E" mode, i.e. the equal variance mode. I could never get it to work on "V" mode [
2011 Feb 23
0
negative binomial latent class regression in package flexmix
Hello list, Has anyone had any luck creating an M-step driver for negative binomial regression for use with package flexmix? I've had a look here: http://cran.r-project.org/web/packages/flexmix/vignettes/flexmix-intro.pdf as well as poking around in the flexmix source, but I haven't had much luck getting anything to work. I can't figure out how to a) come up with an initial estimate
2012 Jun 15
0
Flexmix package
Hi, I am using the package "flexmix" and would like get some assistance. I am trying to run two equations jointly Y1=X1B+E1 Y2=X2G+E2 So that I have X and Y in a matrix format and would like to run the latent class model using flexmix. Though, my problem here is that Flexmix automatically generates intercepts. I have intercept for both of the equations that my X matrix looks like
2011 Dec 21
0
Estimating a latent class multinomial logit regression with flexmix
I am trying to estimate a latent class multinomial logit regression with flexmix. I am not sure if I should do it as follows: m4<-flexmix(cbind(y,1-y)~x1+x2|id,model=FLXMRglm(family="binomial"),data=NPreg,k=2) , where id links each row with the corresponding respondent. Each respondent has 4 alternatives to chose from. y takes the value 1 only for the alternative chosen; x1 and
2007 Nov 20
0
try FlexMix RE: mulitmodal distributions
Hi, Marion, I believe the package FlexMix provides a more generalized version of finite mixture modeling than is found in mclust/mclust02. Please see: http://cran.r-project.org/doc/vignettes/flexmix/flexmix-intro.pdf Karen --- Karen M. Green, Ph.D. Karen.Green@sanofi-aventis.com Research Investigator Drug Design Group Sanofi Aventis Pharmaceuticals -----Original Message-----
2006 Mar 21
0
finite mixture model, using flexmix
Dear R-users, I would like to use the package flexmix to fit latent classes to a regression model. My data are repeated measurements of bernouilli variables so I can use the binomial family link to the glm function. The design is not balanced, meaning that for some individuals in my data set I have 10 measurements or more, for others I only have 5 or even less. My question is the following. Can
2005 Apr 12
1
R Package: mmlcr and/or flexmix
Greetings I'm a relatively new R user and I'm trying to build a latent class model. I've used the 'R Site Search' and it appears there's not much dialogue on these packages On mmlcr, I've gotten it working, but not sure if I'm using it correctly. On flexmix, I can only seem to get results for one class. I'm attaching my code below - if anyone
2011 Feb 28
0
Gamma mixture models with flexmix
I've been trying with no success to model mixtures of Gamma distributions using the package flexmix (see examples below). Can anyone help me get it to model better? Thanks very much. -Ben ## ## Please help me get flexmix to correctly model mixtures of ## Gamma distributions. See examples below. ## library('flexmix') ## ## Plot a histogram of dat and the Gamma mixture model given
2011 Mar 01
1
Problem on flexmix when trying to apply signature developed in one model to a new sample
Problem on flexmix when trying to apply signature developed in one model to a new sample. Dear R Users, R Core Team, I have a problem when trying to know the classification of the tested cases using two variables with the function of flexmix: After importing the database and creating a matrix: BM<-cbind(Data$var1,Data$var2) I see that the best model has 2 groups and use: ex2
2012 Oct 30
1
Data set BregFix in package flexmix
Dear list: I would like to recreate how the artificial data set BregFix was generated in package flexmix (thanks Bettina and Friedrich). The data set is thoroughly described in Grun and Leisch's Computational Statistics & Data Analysis 51(11) :5247-5252 but references to the appropriate seed number(s) are missing (providing these details was certainly beyond the scope of the authors'
2007 Feb 08
1
smartpred depends on fitted() in flexmix?
Hi, I was going through the examples in smartpred. It seems there's an unstated dependency on the fitted() function in package flexmix. n = 20 set.seed(86) x = sort(runif(n)) y = sort(runif(n)) library(splines) fit = lm(y ~ ns(x, df=5)) plot(x, y) lines(x, fitted(fit)) # won't work w/o prior loading of the flexmix package. newx = seq(0, 1, len=n) points(newx, predict(fit,
2013 Apr 23
2
flexmix
Hi, I am trying to understand how to use the flexmix package, I have read the Leisch paper but am very unclear what is needed for the M-step driver. I am just fitting a simple linear regression model. The documentation is far from clear what the FLXmclust function does, but, it in principle could do all I need, however, I do not get sentible results as if I try the following the result is poor:
2011 Aug 24
0
Refit for flexmix
Hi all, Just a small question: After fitting a multivariate mixture using flexmix, I wish to use refit to get the parameters of covariates and their standard errors. However using refit I only can see the components for the first dependent variable. What should I do if I want to see the others? Thanks a lot, Eric -- View this message in context:
2018 Apr 27
0
about combining analysis results using package 'flexmix' and ' mice'
Hi, I am currently using package ?mice? to do multiple imputation for tourist data here. Then the complete datasets (e.g. m>= 100) will be analyzed with a finite mixture model using package ?flexmix?. I have found that it seems no feasible way to combine the multiple results into a final one smoothly using just a few commands. By the way I have seen that package like ?semTools? has such
2012 Apr 23
2
Overlay Gene Expression on SNP (copy number) data
Hello, Can anyone please suggest any packages in R that can be used to overlay gene expression data on SNP (affymetrix) copy number ? Thanks, Ekta Senior Research Associate Bioinformatics Department Jubilant Biosys Pvt Ltd, #96, Industrial Suburb, 2nd Stage Yeshwantpur, Bangalore 560 022 Ph No : +91-80-66628346 The information contained in this electronic message and in any attachments to this
2007 Apr 16
1
flexmix glm warning
Dear R-helpers & Friedrich Leisch, I'm trying to fit a mixture of regression models on attached data set by doing the following: agl <- read.table("agl.txt") mod1 <- flexmix(resp~gng+csc|Subject,data=agl, model=FLXglm(family="binomial"),k=2) The result is a (varying) number of the following warnings: Warning messages: 1: non-integer #successes in a