similar to: mixed model question and using lmer

Dear list, I have the following problem : I want to model a series of observations of a given hospital activity on various days under various conditions. among my "outcomes" (dependent variables) is the number of patients for which a certain procedure is done. The problem is that, when no relevant patient is hospitalized on said day, there is no observation (for which the "number

All, How does one extract the level-1 variance from a model fit via lmer()? In the code below the level-2 variance component may be obtained via subscripting, but what about the level-1 variance, viz., the 3.215072 term? (actually this term squared) Didn't see anything in the archives on this. Cheers, David > fm <- lmer( dv ~ time.num*drug + (1 | Patient.new), data=dat.new )

All, I'm using lmer for some repeated measures data and have specified the contrasts for a time factor such that say time 3 is the base. This works fine. However, when I next use the subset argument to remove the last two time values, the output indicates that the specified contrast is not maintained (see below). I can solve this by creating a new dataframe for the subset of interest

I'm working with a nested model (mixed). I have four factors: Patients, Tissue, sex, and tissue_stage. Totally I have 10 patients, for each patient, there are 2 tissues (Cancer vs. Normal). I think Tissue and sex are fixed. Patient is nested in sex,Tissue is nested in patient, and tissue_stage is nested in Tissue. I tried aov and lme as the following, > aov(gene ~ tissue + gender +

Dear list members, I am new to R and to the R-help list. I am trying to perform a mixed-model analysis using the lmer() function. I have a problem with the output anova table when using the anova() function on the lmer output object: I only get the numerator d.f., the sum of squares and the mean squares, but not the denominator d.f., F statistics and P values. Below is a sample output, following

Hi, I was wondering if I might be able to ask some advice about doing residual plots for the lmer function in the lme4 package. Our group's aim is to find if the expression staining of a particular gene in a sample (or "core") is related to the pathology of the core. To do this, we used the lmer function to perform a logistic mixed model below. I apologise in advance

I am attempting to model data with the following variables: timepoint - n=48, monthly over 4 years hospital - n=3 opsn1 - no of outcomes total.patients skillmixpc - skill mix percentage nurse.hours.per.day Aims To determine if skillmix affects rate (i.e. no.of.outcomes/total.patients). To determine if nurse.hours.per.day affects rate. To determine if rates vary between

Dear R help list, I have done a lot of searching but have not been able to find an answer to my problem. I apologize in advance if this has been asked before. I am applying a mixed model to my data using lmer. I will use sample data to illustrate my question: >library(lme4) >library(arm) >data("HR", package = "SASmixed") > str(HR) 'data.frame': 120 obs.

Hi, I was wondering if anyone could give me advice regarding using the lmer command in lme4 package to do logistic regression (mixed effects model). I use the following command lmer(ISH ~ArrayPathology2, random=~1|PatientID, data=HSDB4.noNA, family="binomial") where ISH is outcome(0 or 1), ArrayPathology2 is the variable of interest(factor), PatientID is random effect(factor), and

Dear R help gurus, I have the following problem and I would be delighted if you could help me. >From a large (1500) cohort of patients we have been taking some measurements (ECG measurements, but its not important). The measurements are ordinal in 4 grades (Grade I-IV, grade IV being the most severe form). Every patients has been measured several times (usually once per year). The

All, The code below is for a pseudo dataset of repeated measures on patients where there is also a treatment factor called "drug". Time is treated as categorical. What code is necessary to test for a treatment effect at a single time point, e.g., time = 3? Does the answer matter if the design is a crossover design, i.e, each patient received drug and placebo? Finally, what would

Dear professors and collegues I need to perform a analysis of dates from a nested experimental design. From "Bioestatical Analysis" of Zar "Bimetry of Sokal" & Rohlf "Design and Analysis of Experiments" of Montgomery I have: Sum (mean(x)_i - mean(x)_T)2 / (a-1) -> var(epsilon) + n sigma2_B + n b (sum alfa_i)2 / (a-1) Sum (mean(x)_ij - mean(x)_i)2 /

I am running a series of candidate mixed models using lmer (package lme4) and I'd like to be able to compile a list of the AIC scores for those models so that I can quickly summarize and rank the models by AIC. When I do logistic regression, I can easily generate this kind of list by creating the model objects using glm, and doing: > md <- c("md1.lr", "md2.lr",

Hello, I'm using aov() to analyse changes in brain volume between males and females. For every subject (there are 331 in total) I have 8 volume measurements (4 different brain lobes and 2 different tissues (grey/white matter)). The data looks like this: Subject Sex Lobe Tissue Volume subect1 1 F g 262374 subect1 1 F w 173758 subect1 1 O g 67155 subect1 1 O w 30067 subect1 1 P g 117981

Hi all, This is partly a statistical question as well as a question about R, but I am stumped! I have count data from various sites across years. (Not all of the sites in the study appear in all years). Each site has its own habitat score "habitat" that remains constant across all years. I want to know if counts declined faster on sites with high "habitat" scores. I can

This question comes up periodically, probably enough to give it a proper thread and maybe point to this thread for reference (similar to the 'conservative anova' thread not too long ago). Moving from lme syntax, which is the function found in the nlme package, to lmer syntax (found in lme4) is not too difficult. It is probably useful to first explain what the differences are between the

I haven't been able to fully make sense of the conflicting online information about whether and how to specify nesting structure for a nested, mixed model. I'll describe my experiment and hopefully somebody who knows lme4 well can help. We're measuring the fluorescence intensity of brain slices from frogs that have undergone various treatments. We want to use multcomp to look for

Dear R Users, I have a question based on my research. I am analyzing reader-based diagnostic data set. My study involves diabetic patients who were evaluated for treatable diabetic retinopathy based on the presence or absence of two pathologies in their eyes. Pathologies were identified using the clinical examination (Gold standard method). In addition it can be identified by taking digital

Dear R users, I'm hoping that more experienced users will be able to assist me in examining the model fit of a mixed generalised linear model. The example using the data 'bacteria' within the MASS package will hopefully illustrate what I would like to acheive; library(MASS) library(nlme) attach(bacteria) # y being output and the trt - treatment group being an explanatory variable.

Dear all, I have three concerns: 1) I am running models with the lme4 package. I cannot find a way to pull out a vector of the fitted values and the residuals. Does anybody know how to do it? 2) How can I nest a random effect variable into a "two-level" fixed effect variable? 3) Suppose I have the following model: y = a + b|c + d + error, where 'a' is a fixed effect, 'c'