similar to: Fitting a Correlated Hazard Model???

Dear R-users, I have two samples with individuals that are in more than one of the samples and individuals that are only in one sample. I have been trying to do a pooled hazard model, stacking one sample below the other, with aftreg and time-dependent covariates. The idea behind is to see aggregate effects of covariates, but need to control for ther effects of same individuals in both samples

Dear All, I'm having just a little terminology problem, relating the language used in the Hosmer and Lemeshow text on Applied Survival Analysis to that of the help that comes with the survival package. I am trying to back out the values for the baseline hazard, h_o(t_i), for each event time or observation time. Now survfit(fit)$surv gives me the value of the survival function, S(t_i|X_i,B),

Dear all, Is there a way to calculate the non-cumulative hazard (instantaneous hazard), which is the product of baseline hazard and exp{beta*covariate} ? I knew in survfit, we can get the estimator of cumulative baseline hazard, but how can we get the non-cumulative one? Thank you very much! Koshihaku -- View this message in context:

Dear R-users, I am checking the proportional hazard assumption of a cox model for a given covariate, let say Z1, after adjusting for other relavent covariates in the model. To this end, I fitted cox model stratified on the discrete values of Z1 and try to get beslow estimator for the baseline cumulative hazard function (H(t)) in each stratum. As far as i know, if the proportionality assumption

Hi everyone. There's been several threads on baseline hazard in Cox model but I think they were all on cumulative baseline hazard, for instance http://tolstoy.newcastle.edu.au/R/help/01a/0464.html http://tolstoy.newcastle.edu.au/R/help/01a/0436.html "basehaz" in package survival seems to do a cumulative hazard. extract from the basehaz function: sfit <- survfit(fit) H

Thanks for sharing the questions and responses! Is it possible to appreciate how much the coefficients matter in one or the other model? Say, using Biau's example, using coxph, as.factor(grade2 == "high")TRUE gives hazard ratio 1.27 (rounded). As clinician I can grasp this HR as 27% relative increase. I can relate with other published results. With survreg the Weibull model gives a

Greetings, I am new to R and have been comparing CPH survival analysis hazard ratios between R and SAS PhReg. The binary covariates' HRs are the same, however the continuous variables, for example age, have quite different HRs although in the same direction. SAS PhReg produces HRs which are the change in risk for every one increment change in the independent variable. How do I

Hello , I am hoping for some advice regarding obtaining the values for the hazard function in a cox regression that I have undertaken. I have a model in the following form, analysed with the package survival (v. 2.34-1) and a log-log plot obtained using Design (v. 2.1-2). For two variables, the lines in the survival curves crossed. The statistician I been obtaining advice from (who does not

Hello, coxph does not use any information that are in the dataset between event times (or "death times") , since computation only occurs at event times. For instance, removing observations when there is no event at that time in the whole dataset does not change the results: > set.seed(1) > data <- as.data.frame(cbind(start=c(1:5,1:5,1:4),stop=c(2:6,2:6,2:5),status=c(rep(

Dear Forum, I have a question about interaction estimate in the Cox model: why the hazard ratio of the interaction is not produced in the summary of the model? (Instead, the estimate of the coefficient is given in the print of the model.) # Example: modINT <-cph( Surv(T_BASE, T_FIN,STATUS)~ NYHA + ASINI + RFP + FE_REC + XX_PR*XX_DISF) print(modINT) coef se(coef) z

Dear R-users, I would like to fit a fully parametric proportional hazard model with a weibull baseline hazard and a logit link function. This is, the hazard function is: lambda_i (t) = lambda_0 (t) psi (x_i* beta) where lambda_0 is a weibull distribution and psi a logistic distribution. Does someone know a package and/or function on R to do this? Thanks. -- M.L. Avendaño [[alternative HTML

I am using a syntax like coxph(Surv(start, stop, event) ~ X, data) to estimate the effect of X, which may change at each measurement (every 6 months). Is there anyone who knows a way to test the proportional hazard assumption in that case? Thank you in advance Jean-François Boudreau Sherbrooke University [[alternative HTML version deleted]]

Greetings -- I would like to estimate a proportional hazard model with a weibull or lognormal baseline. I have looked at both the coxph() and survreg() functions and neither appear (to me ) to do it. Am I missing something in the docs or is there another terrific package out there that will do this. Many Thanks. Carl Mason

Hello, I'm interested in correcting for and measuring unobserved heterogeneity ("missing variables") using R. In particular, I'm searching for a simple way to measure the amount of unobserved heterogeneity remaining in a series of increasingly complex models (adding additional variables to each new model) on the same data. I have a static database of 400,000 or

Hello, all. I have co-opted a number of functions that can be used to plot the hazard/survival functions and associated density distribution for a Gompertz mortality model, given known parameters. The Gompertz hazard model has been shown to fit relatively well to the human adult lifespan. For example, if I wanted to plot the hazard (i.e., mortality) functions: pop1 <- function (t) {

Dear friends, I have used R for some time now and have a tricky question about the coxph-function: To sum it up, I am not sure whether I can use coxph in conjunction with missing covariate data in a model with time-variant covariates. The point is: I know how "old" every piece that I oberserve is, but do not have fully historical information about the corresponding covariates. Maybe you

Dear R help list, I am modeling some survival data with coxph and survreg (dist='weibull') using package survival. I have 2 problems: 1) I do not understand how to interpret the regression coefficients in the survreg output and it is not clear, for me, from ?survreg.objects how to. Here is an example of the codes that points out my problem: - data is stc1 - the factor is dichotomous

Hello everyone, I am a new user of R. Does anybody know how hazard ratios are extracted for each factor level in a stratified Cox proportional hazard regression model? I have a cancer data set where the variable ?differentiation? is a factor with three levels: poor, intermediate and good. I would like to extract the hazard ratio for each grade level and relate it to another prognostic factor.

Dear all, I have been trying to plot hazard function in R for survival data, but in vain. Can anybody help me out in plotting hazard function in R? Dr Suman Kumar -- View this message in context: http://r.789695.n4.nabble.com/how-to-plot-hazard-function-for-coxph-model-tp4637953.html Sent from the R help mailing list archive at Nabble.com.

Dear R-users, I am looking for a function designed to handle parametric proportional hazard models with a piecewise constant baseline hazard (i.e. dummies for annual intervals) and time-dependent covariates since I'm especially interested about the effect of those covariates on the baseline hazard. I tried survreg() but this doesn't seem to work since my data looks like this id/ start/