similar to: using lsoda() and nls() together

Hi all, I try to assess the parameters (K1,K2) of a model that describes the adsorption of a molecule onto on adsorbent. equation: dq/dt = K1*C*(qm-q)-K2*q I know the value of 'qm' and I experimentally measure the variables 'q', 'C', and the time 't'. t C q 1 0 144.05047 0.0000000 2 565 99.71492 0.1105625 3 988 74.99426

Dear Hank, Last question first: really, only you can say for sure if 4e-281 and 5e-11 are small enough; it depends on the units you measure your state variables in. However, this strategy cannot get the state variables to exactly 0. Obviously, you could get closer to 0.0 faster by setting the derivatives even larger in absolute value. You may run into problems with the solver when the

Hi, I'd like to know whether R is capable to assess parameters in a model describing the kinetic of a pollutant adsorption onto activated carbon. A common relation is for instance the Adam-Bohart-Thomas' one: dx/dt = K1 * (qm-x)*C - K2x where {K1,K2} are the unknown paramters and {qm,C} are known parameters Of course I get experimental data sets of measured x as a function of time.

I am running R 1.2.3 with ESS5.1.18 with Windows 98. I am trying to use lsoda in the odesolve apckage and am having problems. Question: The return value of the function of the system of ode's has to be a list that includes first, the ode's and second, "a vector (possibly with a `names' attribute) of global values that are required at each point in `times'." I

Dear Colleagues, Our group is also working on implementing the use of R for pharmacokinetic compartmental analysis. Perhaps I have missed something, but > fit <- nls(noisy ~ lsoda(xstart, time, one.compartment.model, c(K1=0.5, k2=0.5)), + data=C1.lsoda, + start=list(K1=0.3, k2=0.7), + trace=T + ) Error in eval(as.name(varName), data) : Object

I have been trying to make use of the odesolve library on my university's Linux grid - currently R version 2.0.1 is installed and the system runs 64-bit Scientific Linux based on Redhat. I cannot seem to get lsoda working when I define the model as a shared C library. For example, the following snippet uses the mymod.c example bundled with the package: ### START rm(list=ls())

Dear Michael, One key is adjustment of nls optimizer tolerance. I notice it has to be higher than usual, but, I recovered your noisy "known" parameter values with an error of K1 (-7%) and k1 (-6%): #### Miller problem with Dalgaard modifications ## Linares 1/22/2004 ## Solution 1 nls(noisy ~ lsoda(xstart, time, one.compartment.model, c(K1=K1, k2=k2))[,2], data=C1.lsoda,

Hello, I am writing a package with a collection of several models. In order to allow users to play interactively with the models (in contrast to hacking lengthy scripts), I want to put all what is needed to run a particular model into a single list object for each model. Then there will be a collection of functions to run the model or to modify parameters, time steps, integration method ...,

Dear R Gang, I'm interested in using R and the nls package for fitting kinetic models. I'm having some difficulty getting a model specified for nls though. The math for the model that I want to fit is dg(t)/dt = K1 f(t) - k2 g(t) where g(t) and f(t) are measured data at a sequence of times t. K1 and k2 are the parameters of the model. If I solve this, the solution is g(t) = K1

Dear list - Does anyone have any ideas / comments about why I am receiving the following warning when I run lsoda: 1: lsoda-- at t (=r1), too much accuracy requested in: lsoda(start, times, model, parms) 2: for precision of machine.. see tolsf (=r2) in: lsoda(start, times, model, parms) I have tried changing both rtol and atol but without success. I saw the thread in the

Hi, I would like to solve a system of coupled ordinary differential equations, where there is a delay (time lag) term. I would like to use the "lsoda" function "odesolve" package. However, I am not sure how to specify the delay term using the syntax allowed by odesolve. Here is an example of the kind of problem that I am trying to solve: > library(odesolve)

Hi, The code below is giving me this error message: Error in while (err > eps) { : missing value where TRUE/FALSE needed In addition: Warning messages: 1: In dnbinom(x, size, prob, log) : NaNs produced 2: In dnbinom(x, size, prob, log) : NaNs produced I know from the help files that for dnbinom "Invalid size or prob will result in return value NaN, with a warning", but I am not able

Dear List, Wonder if you have some thoughts on the following question using lsoda in desolve: I have the following data and function: require(deSolve) times <- c(0:24) tin  <- 0.5 D <- 400 V    <- 26.3 k <-0.056 k12  <- 0.197118 k21  <- 0.022665 yini <- c(dy1 = 0,dy2 = 0)  events <- data.frame(var = "dy1",time = c(10,15),value = c(200,100),method =

Vince, When that happens, one possible reason is that your DAE is of index > 1, which cannot be solved by daspk. The solver radau, also from deSolve can handle DAEs up to index 3, but you need to rewrite the problem in the form M*y' = f(x,y), where M is a mass matrix. If you do that for your problem, and solve it with radau, then radau complains that the "matrix is repeatedly

I'm getting this error on the attached code and breaking my head but can't figure it out. Any help is much appreciated. Thanks, Vince CODE: library(deSolve) Res_DAE=function(t, y, dy, pars) { with(as.list(c(y, dy, pars)), { res1 = -dS -dES-k2*ES res2 = -dP + k2*ES eq1 = Eo-E -ES eq2 = So-S -ES -P return(list(c(res1, res2, eq1, eq2))) }) } pars <- c(Eo=0.02,

All- I am interested in estimating a parameter that is the starting value for an ODE model. That is, in the typical combined fitting procedure using nls and lsoda (alternatively rk4), I first defined the ODE model: minmod <- function(t, y, parms) { G <- y[1] X <- y[2] with(as.list(parms),{ I_t <- approx(time, I.input, t)$y dG <- -1*(p1 + X)*G +p1*G_b dX <-

Hi All I am getting the above mentioned error when I run the code below. I don't know why because I have implemented the function and I'm calling the function with a parameter. I'm obviously missing the plot ... Can someone perhaps point out the error of my ways? Error: > out<-ode(y=init, times=times, func=G1999, parms=parms, method="lsoda") Error in m_Na(v) : attempt

Hello there, Suppose you want to solve the following system of ODE's (a simple Lotka-Volterra predator prey model) dP/dt = beta*P*V - mu*P dV/dt = r*V - beta*P*V where P and V are the numbers of predators and prey. Now, this is easy to do, but suppose you have a system of equations like this, dP1/dt = beta1*P1*V1 - mu1*P1 dP2/dt = beta2*P2*V2 - mu2*P2 dV1/dt = r1*V1 - beta1*P1*V1

Dear R-users, I'm running an MLE procedure where some ODEs are solved for each iteration in the maximization process. I use mle2 for the Maximum likelihood and deSolve for the ODEs. The problem is that somewhere along the way the ODE solver crashes and I get the following error message: DLSODA- Warning..Internal T (=R1) and H (=R2) are such that in the machine, T + H = T on the next

Hello, I am an R newbie, trying to use lsoda to solve standard Lotka-Volterra competition equations. My question is: how do I pass a parameter that varies with time, like say, phix <- 0.7 + runif(tmax) in the example below. # defining function lotvol <- function(t,n,p){ x <- n[1]; y <- n[2] rx <- p["rx"]; ry <- p["ry"] Kx <-