[R] Query in Cuminc - stratification

kay frances
2008-12-08T13:29:21Z

Hello everyone,

I am a very new user of R and I have a query about the cuminc function in the
package cmprsk. In particular I would like to verify that I am interpreting the
output correctly when we have a stratification variable.

Hypothetical example:

group : fair hair, dark hair
fstatus: 1=Relapse, 2=TRM, 0=censored
strata: sex (M or F)

Our data would be split into:

Fair, male, relapse
Dark,male, relapse
Fair, female, relapse
Dark, female, relapse

Fair, male, TRM
Dark,male, TRM
Fair, female, TRM
Dark, female, TRM

Fair, male, censored
Dark,male, censored
Fair, female, censored
Dark, female, censored

Am I correct in thinking that the 2 "Tests" which will be printed by R
tell us (i) if there are significant differences between those with fair hair
and those with dark hair as regards cumulative incidence of relapse [taking into
account sex differences] (ii) if there are significant differences between those
with fair hair and those with dark hair as regards cumulative incidence of TRM
[taking into account sex differences] ? The ‘est’and ‘var’values are the same
regardless of whether we include a stratification variable or not.

If we do not include a stratification variable the ‘tests’ results will be
different to those when a stratification variable is included and they test (i)
if there are significant differences between those with fair hair and those with
dark hair as regards cumulative incidence of relapse (ii) if there are
significant differences between those with fair hair and those with dark hair as
regards cumulative incidence of TRM.

Just thought I’d double check.
Many thanks,
Kim



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